Are you talking about the McMartin daycare case, circa 1983-4? If so, I heard, and it’s probably true, that the woman who first filed charges was a complete loon, and accused the daycare providers of doing things that were physically impossible to do, and also impossible to do without other kids’ parents realizing something was way wrong.
I think it’s most likely that Oswald was aiming at Connaly.
-Vince Foster: people are still wondering how he managed to shoot himself in the head, then drive to the park where his body was found!
-Ron Brown: he was about to spill the beans-he allegedly died in a plane crash, but wound up with two in the hat!
-The two lads in Mena , Arkansas, who smoked too much marijuana (and laid down with their necks across the railroad tracks
You realize that you just got your name put on a list, right?
Napoleon Bonaparte: stomach cancer? Arsenic?
Marilyn Monroe (hard to believe no one’s mentioned her yet)
The Roanoke colony
The Octavia’s crew
Trotsky
Hoffa
I’d pick Jack the Ripper as the most famous, but one that hasn’t been mentioned yet is Sacco and Venzetti. I still read accounts of this case in which experts claim to have reviewed all the evidence in an unbiased manner and determined the truth. Unfortunately, the revealed truths seem to be evenly divided on whether they were guilty or innocent (or maybe one of each).
I got to go with the Roanoke one…though no one has actually said murder.
I mean you have a colony of people just disappear like that, no bodies, no signs of war, nothing. And everyone just going poof in a winter? Strange
The Black Dahlia was interesting in its own right, I mean a neatly severed woman found in a vacant lot, not a speck of blood on her or around her?
Oh and the Calvi case is of high high regard to conspiracy theorists and a meaty mystery. I am amazed that not a lot of people who love a good whodunnit have yet to hear of it. Hell it practically implicates the Church for murder and invokes secret societies and the like.
This case was solved most convincingly by the agent assigned to the case. He wrote a small book on the subject. Sorry, I don’t remember his name or the book title but I found it at the local library. If you can track it down with this sketchy info it’s a very interesting read.
People just hate to see a good mystery die.
Interesting screen name! Do you know something we don’t? 
You’ve named a lot of good ones, but Lizzie Borden fascinates me.
Definitely the Black Dahlia.
Zodiac Killer a close second.
Also, there is the Green River serial killer, in Washington state, I think, still unsolved.
That’s the one I was specifically thinking of when I read the thread title. I remember reading about that case way back when I first found The Book of Lists. It’s stuck with me this long – probably because it seems like something right out of film noir.
I’m not about to flame you for this. In fact if I were to ask you for a cite, it would be out of my own curiosity, not any doubt shed upon you.
So … cite?
Try this link:
Don’t know if this really qualifies as a murder or not, but what about the Mary Celeste?
I just read about this somewhere. The house he was
imprisoned in had arsenic in the wallpaper - there’s a
theory that prolonged exposure (I think it slowly leeched
into the air) poisoned him.
Is there really much mystery about what happened there?
The word “Croatoan” was etched into a tree…
How about King Ludwig II of Bavaria? Murder or Suicide?
Here:
http://www.grand-illusions.com/napoleon/napol1.htm
I think it was a quiz question at the “Whaddya Know?” site
a month or so back…
I just finished an interesting book on this topic, called The Cases That Haunt Us, by John Douglas and Mark Olshaker. Douglas is the former FBI profiler whom you often see on TV discussing high-profile cases. This book has chapters on Jack the Ripper, Lizzie Borden, the Lindbergh kidnapping, the Zodiac, the Black Dahlia, JonBenet and several others. Douglas kind of breaks down all the available evidence to analyze which suspects/theories are plausible and which aren’t.
Apb9999, what was Octavia’s crew? I tried to look it up on Google, but just got a lot of pages about rowing teams and Roman history.