Forgot to add “River City” to the other monikers for Portland.
Pittsburgh (a.k.a. “da 'burgh”). Where else?
The larger region is known as the Western Slope. We’re a little too far north to be part of the Four Corners. South San Juans. Telluride region. Paradise. La-la land.
A lot of us call our little island “The Rock”. It is pretty up and down - 2400 ft. elevation about 1 1/2 miles from the ocean.
(Orcas Island, WA)
Penniless Park, in the Bay Area.
(Pinellas Park, in Pinellas County, on the west (or good) side of Tampa Bay.)
I thought for a time in the early 2000s that “River City” was a nickname for Washington, DC, because of a line from an Arnold Schwartzenegger film.
I was unfamiliar with The Music Man at the time.
Wigan, where I was born, used to be called “coalopolis” due to the number of mines.
As a student, I lived in Edinburgh, which has the famous “auld reekie” nickname.
Bologna, where I live now, has three nicknames: “la grossa” (the fat), “la rossa” (the red) and “la dotta” (the learned). The first refers to the fact that the town is reputed to have the best cuisine in Italy. The second refers to the red colour of the buildings and the fact that the local government was dominated by communists until very recently (and the region is still very left leaning). The last refers to the town’s university, the oldest in the world.
I once lived in Albany, GA, and they called that area SOWEGA for southwest Georgia.
C-Bus or Cowtown.
(Columbus, OH)
The Gateway to Northern Ontario, just east of The Nickel Belt.
We do sometimes like to call ourselves ‘dirtyrottenchester’. Or, just hell hole.
The Conch Republic or Paradise:cool:
“Central Florida”. Good times.
Oooooh yeeeaaaaah… I vividly remember Orcas Island from the bike trips my church youth group took every summer through the San Juan Islands 
My city, Wenatchee, WA, bills itself as “The Apple Capital of the World”. And continues to do so despite Yakima, WA surpassing us in apple production several years ago.
No, No, No, No, No.
We that live here don’t call it that ourselves. Jerks from other places call it that.
We call it “Cleveland”, or “Greater Cleveland” or “Northeastern Ohio.” We’ll cop to being not too original in our nicknaming, but not to being a mistake.
Lowell, MA is generically called “Mill City” due to all of the large, looming mills around the downtown area. Most of them are slowly being turned into lofts.
Of course, you can live in specific parts of Lowell: the Acre (blech), Pawtucketville (not too shabby, but inconveniently on the other side of the Merrimack), the Highlands (Ok), Belvidere (large, historic houses) or Tyler Park (historic, cute, expensive).
the Gem City
the Miami Valley
Appalachia North
Dayton OH (sadly)
Albuquerque: Known as Duke City.
With the neighborhoods I lived in known as the Student Ghetto and The War Zone.
The Valley for the general area, which is the Tennessee Valley in the Chattanooga area. Chattanooga itself is The Scenic City, Chattown, Nooga, or The Noog.
I don’t know of any for the actual city I live in (Cleveland, TN) other than the ridiculous -vegas suffix that so many cities seem to get saddled with that annoys the crap out of me.
Never heard of #1 but #2, quite often. I’ve called the area “The Redneck Meth-mouth Capitol of the Universe…”