Bushmeat had probably always been associated with risk of disease, but in earlier times these diseases would be confined to remote communities, where they would simmer at a low level (as HIV likely did), wipe everyone out, or eventually mutate to be less deadly.
In modern times, humans are moving into more remote locations (in Cameroon, logging roads deep into virgin forest are a driver of bush meat.) They are hunting animals that have no experience with human and have not had their diseases come into equilibrium with human settlements.
In the meantime, elites have taken up bush meat as a luxury item, while the poor have found it an economical alternative to farmed food. And migrants to the ever growing cities buy it for nostalgia.
New roads, along with increased travel in general, had turned bush meat from a local specialty that has to be consumed immediately to a brisk international trade.