Which speaker set-up should I use? Opinions?

For the past bunch of years, I’ve been performing live music for people (solo) and I’ve been using speaker cabinets mounted on aluminum tripod stands. I’m getting older and hoicking that 50 lb cab up there is also getting old. I’m thinking column speakers; wheel them in with the hand truck. I know there’ll be some loss of bass response, but I’d like some facts and opinions. Thanks.