I’ve seen this behavior first hand a few times, and have to say it’s spooky. Not only are you seeing strange things running around the walls, but some cat is up there for real.
My friends think that kitty is psychic, and is tuning into tripped out brainwaves, but I’m inclined to think the LSD simply creates strange pheramones, turning us into something like human catnip.
Anyone got the straight on this dope?
OK, let me get this straight. You’re tripping, and you want to know why the cat is acting strange. Why the cat, in particular? Why not, say, the lamp? It acts strange, too, while your tripping. My darts always acted weird as well - they left streamers when you through 'em. The walls tend to be a little weird, too, bubbling and waving and stuff.
The answer: the cat isn’t acting weird, YOU are. Try getting in a room with a group of friends, turn the music up, and start laughing uncontrolably at everything. The cat will freak out, trust me.
I’d say that your cat is freaking out because it’s scared. It’s scared bacause you’re acting very abnormally, and the cat naturally assumes that your bizarre behavior is a sign of some kind of huge predator or other major trouble.
Ditto Athena and the Diceman. Back when I was young, stupid, and doing things like tripping, my cats did the same thing they always did when we had a houseful of people over, whether we were drinking, smoking dope, or just watching movies and making racket: they hid under the bed. It could have been that people sometimes missed the mark and peed on them when they went in the bathroom. It could have been that someone thought it might be fun to blow pot smoke into their snouts when they lounged on the back of the couch. They’re acting alright. You’re acting like a freak.
Next time you’re tripping, try asking them. 
Yeah, cats get really strange when you trip. Mine telepathically communicate to me that the apocalypse is approaching, Yahweh’s reign is drawing to an end, the Egyptian goddess Bast is taking over the phenomenological universe, only human beings with housecats will be spared in the coming purge, and aren’t I lucky I have my cats to look after me?
There is a saying “Nervous as a cat in a room full of rockers.”
Maybe he thinks you will fall on him
Agreed Craftsman0004 I stay away from the LDS now, as Spock would say. Thanks for the thoughtful reply.
For those who think it’s just that you or your friends are acting weird and the cats pick up on the manifest, that’s not the case. I’ve seen cats freak even when the tripper is sitting quietly, with no music and hardly any conversation or whatever else going on.
Cats are very observant animals. They may not understand or have a thought process that tells them “Hey - there’s something wrong with that dude.”, but they do seem to have a strong instinct for avoiding things or being cautious of things that are different. We’ve all seen how cats react when you bring home something new - cautiously walking up to it, sniffing gingerly, then finally scenting it. Now, couple that awareness and caution of new things with a person, possibly a stranger to the house, who is a drugged-out freak screaming “Dude!” or “You da man!” or whatever else it is that people do when they are stoned…and you can see why the cat wants the person to stop screaming, or go away, or drown in their own vomit…whatever.
Even if you are quiet about it, they seem to notice. Mine can tell if I am sick, due to my diabetes or otherwise. They also will come up and seem to know to comfort me if I am down. Or maybe they’re just hungry…