I think you can make the following assumptions for most people:
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A bed with one side against the wall takes up much less space than a bed free-floating in the room, so it will be against a wall.
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If two people are sleeping in the bed, you want the foot and sides of the bed free, the sides because you don’t want to have to climb over each other and, for those without footboards, the foot because it’s useful to sit on when putting on your shoes or pants (not in that order).
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If the head of the bed is going to be against a wall, then, there is a 75% chance that that will be putting your head away from the door. I think in reality it’s even more common than that (though not in my guest room, I just realized) because when people have a pretty bed and/or pretty bedding, they want the head of the bed to be visible from the hall just because what’s the point of having a pretty bed and/or bedding and having it all made up properly when your mom visits if she can’t see it when she walks by?