My PBS station is W-PNE, which I always think of as a flower.
How about the N.E.E.K.C. (Annie E. Casey) Foundation?
I always used to abbreviate “B4” in my class notes.
There’s also science fiction’s (and the SDMB’s) Ralph 124C41+ The plus is extraneous, but the rest says “one to foresee for one.”
Just popping in to recommend this! Also the sequel, CDC.
Absolutely great fun and very creative:
V F E-10 D L-F-N
α ב
There was a thread sometime ago about people who heard NPR’s sponsor The *Annie E. Casey *foundation as The NEEKC foundation…
I know where you live! (That was my PBS station when I was a kid. 
)
Eh. . . ya don’t say? (OK, I didn’t actually point to the link, but notice the first hit.)
I went to a restaurant in Tampa, FL, that was named CDB’s. When we asked about the name, the waiter brought out the book, CDB. I think that there a few in the chain now.
Since I haven’t seen it, I’ll add the always popular:
XTC = ecstasy
Also a British band from the 70s/80s.
My favorite is only valid if one lays on one’s Boston accent with a trowel:
PSDS
Pierced ears
And Canadians spell their country’s name “CND.”
C, eh? N, eh? D, eh?
OK, an actual example:
NMNE
S, V F no bananas.
V F no bananas today.
World’s shortest poem:
Caesar’s observations for posterity upon being stabbed by Brutus
U 2?
YY U R
YY U B
I C U R
YY 4 ME!
Too wise you are,
Too wise you be,
I see you are
Too wise for me
If you see Kay
Tell him he may
See you in tea
Tell him from me.
- James Joyce
If you seek Amy
- Britney Spears
My seventh-grade math teacher taught us this nifty mnemonic: Laryngitis, Call Dr. Merrit.
Oicur12
E Zed E Zed? 
Common license plate: IXLR8.
My wife has two good friends from different African countries, and both have names that sound like strings of English letters: Ije (EJ) and Elodie (LOD). It seemed enough of a coincidence to make it a mild joke among the three of them (EJ and LOD didn’t know each other except through my wife.)