"worldwide" Plagues in history?

I say “worldwide” to mean a large geographic area that was interconnected somehow.
Is there any historical evidence of mass death due to disease (or other natural phenomena) where a significant portion of the population in a socio-geographic area was affected aside from the black death in Europe? (Im thinking in places like China, or Middle East. Basically, anywhere with written records going back into antiquity).

PS.
I’m really having trouble wording this question clearly. Hope its understandable.

The 1918 influenza pandemic spread through all continents, and had a higher toll in pure numbers than the Black Death.

There are two that come to mind immediately. Excuse the Wikipedia links…

The Spanish Flu pandemic of 1918-19 killed tens of millions of people worldwide, more than all of World War I.

Smallpox and other diseases killed up to 90% of the inhabitants of North and South America after European contact.

Yep.

http://www.stanford.edu/group/virus/uda/

Crap. You guys are fast :smiley:

Yup - and I even avoided linking to that Stanford site because I thought somebody else would link to it first!

Ah yes, a 1918 style death virus.

This cite disagrees.

Huh?

Another devastating one from earlier in history was “Justinian’s Plague” ( named after the last great East Roman, as opposed to Byzantine, Emperor ), which is surmised to have started ~540 C.E. in central Africa and lasted until at least 590 ( or 767 depending who’s counting ), spreading throughout the Mediterranean and Near East, killing many millions ( the exact numbers are in dispute, but regardless were huge relative to population ). It’s considered one of the big reasons ( in addition to the simple ruinous cost of his wars ) that Justinian’s attempt to rebuild the universal Roman empire, particularly in the west, proved somewhat ephemeral.

  • Tamerlane

Hie thee down to your public library, and check out a copy of Rats, Lice, and History.
Many pandemics are documented therein.

Beetlemania

Beatlemania.

The Black Death lasted far longer than 4 years.

Right before that was the Athenian plague, 5th century BCE. Poor Pericles. Not exactly “worldwide” but well documented nonetheless.

Plague in the Ancient World (which also covers the Justinian Plague)

Beaglemania.

I just thing those doggies are soooo cuuuuute!
What?

Ahem. You were blinded by the panda. :wink: