Worst onscreen (fictional) destruction, by city

Rodanne destroys Tokyo.

Atlanta didn’t do so well in Gone With The Wind.

The OP excluded songs, but NYC is not in good shape (except Queens, apparently) at the end of Billy Joel’s* Miami 2017*.

The OP also excluded historical events. :wink:

Doh! At least it was in a work of fiction.

Hollywood gets destroyed by a sharknado.