I had GPODNIS on my rack, and room to play the S at the end of my opponent’s ZOOM.
I think I remember every single Scrabble bingo triumph in my life, and now I have a new one: playing PONGIDS for a total play of 152, including the points for ZOOMS and the 50 point bingo bonus.
I was happy about turning ZING into UNFREEZING recently, stretching from red square for 72, I believe.
I don’t remember what I scored but I was able to play OXIDIZE once.
Playing Super Scrabble, I had two blanks, two Zs and built off of a pre-existing P to get “pizzazzy” with a Z on the double letter and the Y on the quadruple word score which also completed the word “jumpy”.
Kwyjibo
I once was able to stretch between two triple-word scores and use all 7 letters for QUALMIER (I believe it was the E that was already on the board).
I recently played my first game of scrabble in about 25 years, and it took all of one game for me to recall why I hated that game so much. It isn’t about having a good vocabulary or making long words; it’s about getting the right tiles, knowing that Qi and AA are words, and being able to add S or Y. When adding the letter Q on a triple letter score to an I nets you more points than Cadaver, something is wrong.
And my answer is “jonquils”
According to the Scrabble app on Facebook, my best word was VESTIGE for 96 points. I know I’ve gotten at least 140+ point word in Scrabble knock-off Words With Friends, but pretty much all the point totals are higher in that game.
How about the web game Bookworm, can I mention Bookworm?
Because I got “Exclusivities”!
Actually, it wouldn’t accept it because it was too long, so I had to go with “Exclusivity”.
I was pretty pleased with myself.
I don’t know what my best word was but I once beat a native Spanish speaker in Scrabble in Spanish, and I barely know any Spanish past Taco Bell-level! To be honest, though, that game was kind of like watching one of those Thai boxing matches where both fighters are blindfolded.
My first game of Scrabble ever, first rack of tiles ever, I played all of them on my opening move.
It’s been entirely downhill since.
I can’t remember the exact details, but whatever I did was a legal move. I put an X next to an A, and added an O to the X. The X happened to be on a triple letter square, and I got points for two words (ax and ox).
My opening rack allowed me to play UNICORN as the first play of the game.
Beyond that I’m lucky to spell DOG or CAT. 
“Why you little…!”
This one is easy for me. Playing against a rather attractive woman and losing quite badly I played my last 7 tiles to spell VAGINAS and win the game. The glory was exquisite.
Was I the only one to read the OP and immediately think the answer was going to be “dopings”? I probably was, actually, as I guess all you word nuts would instantly know that’s not a valid word :). Perhaps it should be, for example: “How many dopings [doping scandals] will it take for cycling to clean up its act?”.
Sorry I giggled at the title of the OP - a message board I belonged to before used “Scrabble” as a euphanism for “sexytimes.” Long story.
Once I played a strip Scrabble game and won twice.
It was just two players and the rule was if you made a play for 25 points or more, your opponent removed an article of clothing OR you could put one back on. I think I ended with >400 points; I was highly motivated.
Among many others,
Scored over 700 points twice.(IRL,and against a decent player both times)
Had a 6 turn span where I scored 424 points.
What? It’s a perfectly cromulent word.