Oooohhh goody… another holy war over what constitutes a True and Righteous hamburger: ::knives out::
Sure you can… you can season it 
For me, if I want the unadulterated taste of meat I’ll skip ground beef completely. Ground beef is usually chuck, so when I’m hankerin’ for some meat I’ll grill up some steaks or do a roast in the smoker. A brisket or a pork shoulder done low and slow in a charcoal smoker is absolutely divine. Hell, just a simple pot roast done in a Dutch oven with some potatoes, carrots, and onions is pretty hard to beat, too.
For hamburgers, the taste of ground chuck by itself is… unimpressive. Personally I’ll take a couple of pounds of ground chuck and add A-1 sauce, Worcestershire sauce, maybe some BBQ sauce, some mined garlic and onion, and maybe some Montreal Steak seasoning. Mix, form into ~1/2 lb patties, and grill on a Weber kettle (the only way to cook a burger) until there’s a light sear on the outside and only the tiniest hint of pink inside. For the last 2 or 3 minutes on the grill add a slice of muenster or sharp cheddar, depending on the pickiness of the eaters. I like muenster, my wife likes cheddar. They come off the grill juicy and delicious. Sometimes I’ll sprinkle some more Montreal and slather on some BBQ sauce when I first toss them on the grill for some extra yumminess. Serve with caramelized onions and a stack of kosher dill slices on a decent potato roll or, better yet, some SF sourdough rolls. I have no use for raw onions, raw tomatoes, ketchup, or mustard and the addition of any of those, especially the onion or tomato, will ruin my burger. I realize this makes me a heretic, but whatever.
Another yummy variation is to smoke your burgers. An hour on the WSM with some hickory makes some world-class – whoops, sorry. Got drool on my shirt. Smoking them requires some advanced planning and an afternoon free especially in a charcoal smoker because you need time to get the smoker temp stabilized. But the results are worth it.
I confess I’ve done that numerous times for big family get-togethers and Boy Scout cookouts and the like. I try to liven the patties up a bit with BBQ sauce and / or Montreal Steak, but in a pinch those pre-made frozen patties that you can simply plop on the grill are sufficient for a quick and easy afternoon BBQ.