Okay, Eddie Murphy played twin brothers in Bowfinger.
To extend the thread, have there ever been non-identical twins in the same film?
Right, and that’s exactly why I would never post how Robert Picardo played Voyager’s Emergency Medical Hologram, an “evil” EMH in the two-part episode “Equinox” and several dozen repurposed EMHes in a later episode.
Because that wouldn’t be respectful of twickster’s wishes.
Well, there’s the Witch Mountain series, for starters… finding movies in which the siblings are brother-and-sister (and have some creepy powers) is probably a lot easier than finding ones with same-sex fraternals.
I do not believe they were twins. Tony was a couple of years older than Tia, at least in the films.
The aforementioned “Big Business” with Tomlin and Midler had as its premise that they were two sets of identical twins inadvertantly split up at birth. So the mixed sets of identical twins believed they were non-identical.
“Basket Case” also featured non-identical twins.
Roger Moore AND Michael Caine played two pairs of lookalikes in Bullseye
Roger Moore also played his own duplicate in The Man Who Haunted himself
Anyone wanna count the lookalikes in Doctor Who?
1st Doctor had a robot double in The Chase
2nd Doctor was the double of a ruthless dictator in The Enemy Of The World.
4th Doctor was cloned a couple of times
Sarah Jane, Harry and the Brigadier had android duplicates.
5th Doctor had Omega copy his form. Also an android duplicate.
Nyssa met her “twin” in 1920’s Earth.
Martha was the cousin of a character from an earlier episode, played by the same actress.
And probably a couple of dozen other times.
And Jet Li played a multitude of versions of his character in The One.
All the actors in Sliders played different-universe versions of their characters, but Cleavant Derricks’s own twin sometimes played the alternate versions of his character.
Speaking of sliding, Gwyneth Paltrow played two versions of her character in Sliding Doors.
And also, the EMH on the Enterprise-E in “First Contact.”
Sorry, twickster. 
**Aidan Quinn ** played a pair of identical twins (one good but boring, the other a sexy bad boy) in the delightfully trashy TV-movie Lies of the Twins.
Actually, IIRC, the whole thing played like a de-Cronenberged near-remake of Dead Ringers, with very similar story, only without the icky, mindbending perversities. The nice-guy twin was a doctor (not an ob/gyn, but a psychotherapist) the bad one was a bad influence, and Isabelle Rosellini was the exotic Euro-beauty in the middle. And in a nifty bit of what must have been stunt-casting, Hurd Hatfield (of the classic B&W The Picture of Dorian Gray, which had a doppelganger theme) has a small role.
it’s been a while since I’ve seen the movie, but didn’t Lizardo go mad and become Whorfin? so it’s the same character, no?
There was a made-for-TV version in which they were twins. This version had almost nothing to do with the original version, so it is very easy to forget.
[del]Did anyone mention Eddie Murphy in the remake of the Nutty Professor and it’s sequel The Klumps?[/del] never mind - none of his characters were twins
I seem to recall something about fraternal twins in a movie with Arnold Schwartzenegger and Denny DeVito…
I think it was called The Bus That Couldn’t Slow Down.
In the very creepy Soseiji, Masahiro Motoki plays twins separated at birth.
You know, I used to wonder how they managed to find someone that looked that much like Derricks without actually being Derricks (I’m thinking primarily of “The King Is Back”). This explains it. It does bother me that they’re not identical, though. All the other doubles are.
Does Jack Warden qualify for playing Roy and Luke Fuchs in Used Cars, or were they simply brothers as opposed to twins?
How about Michael Keaton in Multiplicity (1996)? He clones himself and then his clone makes new clones of itself in return. There are about five or six Keatons in that film.
She played twin sisters Isabelle and Angela Dodson. Isabelle was committed to an asylum, Angela was a cop.
Oh, and that crazy guy from the VW commercials (Peter Stormare) “Representing Deutschland” played a sufficiently creepy Lucifer.
In the 1964 series, the unnamed cartoon actor who played Underdog/Shoeshine Boy also played his evil look-alike, Tap Tap the Chiseler. Wally Cox did Underdog’s voice and narrator George S. Irving voiced Tap Tap, but I submit that the versatile cartoon actor who doubled (tripled?) as Underdog/Shoeshine and Tap Tap brought as much to these complex performances as did Cox and Irving.
When fighting ignorance I am not slow,
So it’s hip, hip, hip, and awaaaaaaay I go!
Christpher Knight played Peter Brady and his “twin” Arthur Owens in the Brady Bunch episode Two Petes in a Pod