Here in NE Ohio all the drugstores I can think of have the entryway on the corner of the store. Most have an actual clipped corner with the doors on the diagonal wall. Even an existing store in Lakewood that got remodeled moved the doorway to the corner, although in that case they did not clip the corner. Other stores do not do this. Dollar stores are just as ubiquitous and they leave the doorway wherever it was when they moved in. It’s like one architect is doing all of them.
My grandson worked at a Rite Aid and he said it did make for a great view down each wall from the register.