It’s a trope that in male/female pairings, the brawn will be the guy and the brain will be the girl. If there’s a split, that is. I’m thinking of innumerable TV ads, Moonlighting, Anne McCaffrey’s Ship series, etc.
Are there any examples of this being reversed? Where the brawn is the girl? And yes, I’ve checked TVTropes. They only give one, and that’s in a super-hero universe.
“We’re a team. I’m the brains, she’s the muscle.”
Will and Grace. Will is the smart one and, several times throughout the series, Grace is shown to be very strong or at least strong then Will (whose muscles you can see through his tight shirts).
Weatherby and Helena in DOA: Dead or Alive.
Buff the Vampire Slayer (superhuman-level strength) and Giles (educated librarian and researcher of all things mystical).
Boy detective Encyclopedia Brown has a girl bodyguard named Sally, to protect him from villainous Bugs Meany.
Oh, and Angela Bassett is the muscle behind Ralph Fiennes’ operation in the movie*** Strange Days.***
I was just going to quote that myself, actually.
Circuitry Man - the couple featured in this tongue in cheek post apocalyptic film has the female partner a bodyguard/organized crime thug and the male partner a very cultured and fey male prostitute. If it changes anything he is a non-biological android of some variety.
The Avengers.
Sarah and Chuck in the early seasons of Chuck.
Baltar and Number Six from Battlestar Galactica. He’s a 5’8" super genius and she’s a 6’ (in heels) bond artifical human with, if not super human strenth, still pretty strong.
Leverage - they have a male character who’s the brawn, but also a female character who’s seriously athletic and extremely strong, and their in-house geek is male.
Also, Kara Thrace and just about anyone.
On “Dark Angel”, Jessica Alba’s old TV series, her character Max was the superhero and the guy in the wheelchair with the computers (who grew up to be Agent DeNozo on “NCIS” 
) , was the brains.
Castle and Beckett in Castle.
While it wasn’t a regular part of the series, the title character on Xena: Warrior Princess occasionally teamed up with a man who possessed knowledge or specialized skills that she lacked. There were a few episodes where she needed the help of Autolycus (Bruce Campbell), the self-proclaimed King of Thieves, to steal something or break into a secure location.
Gina Torres was muscle in the Firefly show.
In some ways, all of Xena could fit the OP (Xena = brawn; Gabby = brains).