I’l let it slide this time 
Ive been up for over 32 hours, I tend to get testy without sleep. 
Not to anybody world-famous, no. But some of my relatives show up in Spanish newspapers somewhat regularly. One of my great-uncles has been dead for more than 10 years but other medical professionals still speak of him to me in awe - even ones who never met him in person.
NFL quarterback Jeff Hostetler is a very distant cousin of mine.
Will I be seeing you at the next family reunion? I too, am related to Jesse James on my father’s side.
When I was in 3rd grade we had to do our family trees for a project. My classmates didn’t let go of my Jesse James connection for the rest of the school year.
Well, according to my mother our family is related to the Windsor dynasty through the Drummonds, a famous family of Scottish bankers. Don’t know if it’s true (which would make me something like a Cousin 24 times removed of the Queen), but I think that might count.
Any amateur geneolagists willing to trace the Drummonds?
Not really famous, but nationally know in some circles…my mother’s cousin is Joe Servello, a fairly prolific illustrator.
They made a movie about a distant relative of mine: Louis “Lepke” Buchalter. I believe my grandmother’s sister married one of his brothers.
My great uncle (father’s uncle) owns a large chain of resturants which bear his name.
Apparently, one of my great-great grandmothers (might be another great in there) held the Guiness Book of World Records title for having the most grandchildren.
Woo Hoo! Two claims to fame!
Ahem.
http://en.wikipedia.org/wiki/Paul_Bostaph
Also, Samuel Bostaph
http://www.udallas.edu/economics/faculty.cfm
who was nominated for the Nobel in Economics.
Finally, my family was once quite wealthy, owning a steel foundry in Pittsburg, a coal mine, & quite a bit more.
Alas, the dough is kaput. 
Funny, a relative of mine is acquainted with Bill Murray’s sister. The details of how they wound up meeting escape me. She’s a nun, isn’t she?
Supposedly, I’m somehow related to one of the cast members of Howdy Doody (Bob Smith, I think… never seen an episode).
Finally, I used to work for a relative of Wesley Clarke.
So yeah, I pretty much got nuthin’
My son is related to Bart Starr and my grandfather used to deal poker for John Dillinger. Other than that, I got nuthin’.
Otis Redding was my cousin.
Alfred Hitchcock was something like my great- great- uncle (well, uncle a couple of times removed both backwards and sideways).
Ain’t it awful? My great grandfather (my father’s maternal grandfather) had a lot of money. He was going to go out to Iowa where he already owned 240 acres and buy up a whole passel more land. He went down to the Binghamton, NY RR station, bought a ticket to Cherokee, IA., sat down on a bench to wait, had a heart attack and died. I’m not sure how the money was dissipated, but it was.
My maternal great-grandmother was a niece of President William Howard Taft.
I’m a direct descendant of Bathsheba Spooner, the last woman to be hanged in Massachusetts.
Tatum O’Neil is some sort of cousin on my mother’s side. I heard she’s making a comeback on TV or something.
I was wondering about that one.
I’m supposedly related to Frank Gorshin, although I’ve never seen any documention proving it.
There’s talk that I’m distantly related to the Pope (the last one, not the now one). However since my whole family’s been atheists for generations we’re not particularly impressed with that.
One the other side (the distaff side) we (the family, about a hundred years ago, so I wasn’t there) changed our name so as not to be associated with a certain uncle who was an embezzler. I guess that’s a kind of fame.
Again, no relatives here…but my dentist of 15+ years is the father of Amanda Bynes, and I graduated with her brother.
It was a trip watching Amanda grow up. They had a wall in the office that had her pics all over it. She liked to get her pic taken with celebrities, so it was covered with images of her standing next to everyone from Phil Hartman to Dustin Hoffman to her costar Frankie Muniz. Then she got the Amanda Show, then the movies, and away she went.
And took my awesome dentist with her!! He retired last year so he could travel with her to her various film locations. BOO!
And a little interesting comment he told me at the last visit: “sigh Laura, never let your kids get into show business.”
My aunt (dad’s sister) was married to Sam Snead’s brother. But technically I’m not related…