Gabriel’s Gate also does a good (maybe not the best, but GOOD) beef on weck, so it’s a good choice to knock out both wings and beef on weck.
For drives, there’s the Seaway Trail. (If you liked Cell Guy’s Frank Lloyd Wright suggestion, you can take this route down to Graycliff.)
I might get drummed off the SDMB for suggesting this, but there is a weird historic community of spiritualists in Lilydale, which is popular with my mother’s set. For those of us who don’t buy into the woo woo of it all, it’s still somewhat interesting in terms of the history of spiritualism. Lilydale is in Chautauqua County (go me, I spelled that right on the first try!), home of the original Chautauqua Institute which is pretty to stroll around in.
If you’re into Arts & Crafts and antiques, the Roycroft Campus is in East Aurora, NY, and that is pleasant, plus they have a cute Main Street, with Vidler’s, an old-fashioned five and dime store.
When you said spry, I don’t know how spry exactly you mean, but if she’s very spry you could check out Kayaking in Buffalo harbor which is more fun than it sounds.
If you like jazz and like going to unusual music venues, there is the Buffalo Colored Musicians Club (warning - web site has sound, and the calendar of events is out of date so you’d have to call).
Free tours of Buffalo’s City Hall are held daily at noon.
Maybe I am a huge dork, but in Niagara Falls itself, they used to offer a tour of parts of the power plant which was incredible, but I can’t find it online now so perhaps it’s no longer available (I will keep looking, but if you come across it, it is definitely interesting).