Well, not in space, really, but at least in zero G:
https://www.yahoo.com/news/watch-cats-handle-zero-gravity-153000248.html
These cats are not happy. Their tails are fluffed out and they’re flailing for support and control. The last shot of the Russian video says it all – the poor cat is clinging onto the strap it’s managed to snag for dear life.
I suspect that cats accustomed to gravity would be as cool and collected as they are on the ground “I meant to bounce off that wall” – but these cats are clearly taken by surprise when their usual expectation of normal gravity was defeated.