“Don’t you ever get sick of being right?”
Bingo
Wouldn’t have remembered it without the name, but Dexter is a dead giveaway.
The Philadelphia Story
Bingo! 
“You, and you alone, must recognize our enemies, the forces of ambition, cruelty, arrogance and stupidity! You must recognize them. You must destroy them! You must tear them out as you would a malignant growth, and cast them from the surface of the Earth!”
No one guessed these, so:
The first is from Beyond the Forrest. The iconic line from that movie was of course, “what a dump!”
The second is from Who’s Afraid of Virginia Woolf. Elizabeth Taylor impersonating Bette Davis’s line from Beyond the Forrest.
Ironically, most people misremember Davis delivering the line as Taylor said it.
“If it bleeds we can kill it.”
Predator
correct
“No one makes me bleed my own blood.”
“It figures it"d be something like this.”
Damn, I can hear the quote in my head, but can’t place it.
" Well, if there wasn’t it’d be an awful waste of space."
" See, I belong to a certain secret society. I don’t believe I gotta mention its name.
“Nuthin’ takes five minutes!”
Yeah? Well, this whole world stinks, Francine, so get used to it! You and that big nose of yours are starting to get on my nerves. Snortin’ around the place like a goddamn anteater. I’ve about had it with you! Gimme that drink!
“Wow, 18 years of nothing, and now twice in one day! What a place!”
O Brother Where Art Thou?
“You gonna bark all day, little doggie, or are you gonna bite?”
Reservoir Dogs
Indeed