Beat LA!
“…acts like she’s the Queen of Sheba.”
Chicago style.
Aberdeen Angus.
Bombay duck.
Jerusalem artichoke.
Vienna circle.
Only part of a city, but: Bronx cheer.
The Bronx
No thonx!
-Ogden Nash
oops/
“We’re not in Kansas anymore”
(oops, that’s not the name of a city.
But I think it still counts 
)
“Take that, East St. Louis!”
In Australia, the location of somewhere which is a long way from anywhere can be referred to as “the back of Bourke” (Bourke being a town which is itself a long way from anywhere).
Stockholm Syndrome.
“Goodnight Vienna”
“It’s gone a a bit Weston-Super-Mare”
(When things go wrong’ named after an unlikely sounding Somerset coastal resort; just a WAG, but maybe an elongated form of ‘mare’, itself a contraction of 'nightmare.)
Brummie Screwdriver
(A hammer, Brummie being ‘from Birmingham, UK.’)
(An English county rather than city)
“Up the wooden hill to Bedfordshire”
(An old way of telling children to go to bed.)
In the same spirit, a Hollywood stop.
“Road to Damascus” experiences.
“The Chicago Way”
Holy Toledo!
There used to be a bit of sartorial splendor called the “Full Cleveland”. It was around the same time as polyester leisure suits.
Chicago politics.
Or “Whoop Whoop,” which for some reason I thought actually existed. Google Maps tells me there’s a Whoop Whoop Road in Queensland, but otherwise no dice.
My dad used to say some things were “more crooked than the road to Weirton”. Referring, I believe, to Route 22 from Pittsburgh, which is pretty much one curve after the other through the mountains.
“Boston aunts” - unmarried women that lived together in a previous generation (or two by now, I should think) but weren’t really related. We were all supposed to pretend that they were just friends who decided to be spinsters together and share the rent.
Reminds me of a Foghorn Leghorn quote that always cracks me up:
“That girl is like the road from Dallas to Fort Worth. No Curves.”*
*The joke, of course, being that Dallas and Fort Worth are near enough together to usually be considered one big city by many folks, to the point where both cities share an airport.
“The gates of Vienna”?