TREACHER (tReacher)
++++
Colossal helium nuclear bomb. (9)
HERCULEAN (he + nuclear)
Have you done any damage to the drug? (7)
ANODYNE (anagram)
+++++
My former partner always had their head up their ass. That’s why we’re at a crossroads.(5)
Try this:
The unAmerican asshole took my former partner in. That’s why we’re at a crossroads.(5)
Expat? ( fits overlap, letter count, evoked by unAmerican and former partner, has a cross in it; otherwise spitballing)
Nexus? ex in N(for no) US?
Nexus is correct (A - nus, + ex).
Your puzzle Biotop
NEXUS
+++++
Concert film assignment pokes fun. (4, 6, 5)
STOP MAKING SENSE (anagram)
+++++
Is a lemon used for wheat flour?(8)
SEMOLINA (anagram)
To insert prop in a, in a private setting without first consulting Victor, is tasteless. (13)
INAPPROPRIATE [IN A P(PROP) RI(-v) ATE]
+++++
Wept upon endangered anteater’s ID. (4-7)
TEAR-STAINED (anagram)
Madame, 'e made beans in a pod. (7)
EDAMAME (anagram)
+++++
Why do lemurs run away from music?(6)
Why do lemurs run away from music?(6)
MELODY (reverse container)
+++++
Energetic, feisty, damn icy! (7)
DYNAMIC (anagram)
A so-called vulgar term for Irishman can be cordial. (8)
AMICABLE (a+MICK+able)
The elder used a Nazi code machine in his trickery.(11)
LEGERDEMAIN? (elder + ge + main)
gemain is an anagram of enigma. Carry on, Knowed_Out.
OK, research shows that Enigma = Nazi code machine, so elder + enigma.
A Tweet shines mixed with a Beatles cover song. (4, 3, 5)
AIN’T SHE SWEET - anagram of A TWEET SHINES
Astronaut John Glenn drank a backward gnat (4).