Yes, having different unit systems around does interfere with design, here in the US. The rest of the world exists in SI (the international “metric” units based on meters, kilograms and seconds) but the US spends a huge amount of extra money on the luxury of nobody having to change their units right now. Those of us caught in the middle see this the most.
I’m a scientist who’s expert in a particular element of machinery and I work with a few dozen design engineers helping improve designs. This problem is a mess.
First, there are conversions between different units. Lengths are pretty easy because an inch is exactly 25.4 millimeters. But the units for heat transfer get extremely messy and there are very many possible units (over 200 I think) for heat transfer coefficient, to give one example. It is a great deal of extra work to convert all of these things when comparing, say, insulation materials available from various manufacturers. Each of these steps carries the possibility of error, and this is true also for the various manufacturers, so their own specifications sometimes have errors (in fact in some cases they will give their specification in more than one unit, and these will contradict each other).
Second, there are all kinds of things we need to buy that come in specific dimensions, such as bolts and rivets and dowel pins and bearings and pipe fittings. Because we may have to use subassemblies based on different units, we need adapters between all these different systems. When we try to test different subsets of a system or when fixing things, we may wind up stopped in our tracks because we need some obscure adapter, even though we have hundreds of things here whose only purpose is to adapt between different unit systems, because the variety of things you could need is mind boggling.
Third, the need to behave globally makes it pretty hard for a company to stick with Imperial dimensions, but the availability in the US of construction materials in regular SI dimensions is more limited. We wind up working in something called “soft metric”, which is a system where you buy Imperial sized raw material and cut SI dimensions into it. Of course this design can’t be reproduced in the rest of the world, where they don’t have Imperial sized materials.
Fourth, those of us that do a lot of science deal with a wide variety of equations that make very simple sense if they are done in what’s called a “coherent unit system”. SI is coherent, and Imperial is not. The equations work in a straightforward way in any coherent system (not just one). However they require all sorts of extra constants, which are basically correction factors, to be used in a non coherent system.
I could go on and on. But, yes, this is an absolute mess, and it’s woven into the foundation of all the technical work that happens in the United States. People who work in any other country typically don’t mess with any of this at all, but here we carry this extra burden – and it’s no goddam fun at all.