Absolutely. I consider driving under the influence of any chemical (recreational, medical, etc.) that impairs necessary functions (alertness, judgement, reaction speed, coordination, etc.) for controlling several tons of vehicle seriously irresponsible and am comfortable with significant penalties in cases where the offender CHOSE to drive impaired. Getting blind-sided by an unexpected reaction to an unfamiliar chemical or having been given said chemical without one’s knowledge or permission* would, of course, be another issue. Intent to be impaired is the significant factor there.
*As in this thread from last year. Summary: bride and caterer thought it would be a marvelous idea to serve the guests pot-laced food without telling them. People wound up in ER because they had no clue what they’d ingested and/or were having problems with the dosage, and I’ve always wondered how many of the guests ran into problems such as surprise DUI or failing employment-related drug testing.