I think one problem is perception - just because someone perceives something it doesn’t necessarily mean it exists. Optical illusions are an example. One can easily perceive something that doesn’t exist, or something that is really part of something else but we only perceive part of it.
Our perception of a soul, even if all we are talking about is the conciousness most of us possess, does not preclude that soul from being an epiphenomenon of the brain.
I’d have to agree with pldennison that general anesthesia is evidence for materialism, as are the fact that there are no recorded cases of brain dead individuals returning to life to tell us about their experience after death.
Dualists or idealistic monists (people who believe matter arises from conciousness, if I have my terminology right) use Near Death Experiences (NDEs) as evidence of mind/soul surviving bodily death, but I believe that inherent in their name is a qualifier of this evidence - they are Near Death Experiences, not Death Experiences. Of course I understand terminology is not always useful as an argument like this, but in this case I believe it is valid as people who come back are not brain-dead.
Also used as evidence for mind being separate from materialism are mind/body healing (e.g. the placebo effect), reincarnation stories from children who cannot know (from this life) the details they proffer about their prior lives, and psi (psychic phenomenon, telekinesis, remote viewing, etc.)
Mind/body healing is not troubling to me (a materialist), as I believe the mind to be an emergent property/epiphenomenon of the brain, and the brain is a part of the body. Thus, it makes sense that the brain can influence the body’s healing systems, and the placebo effect makes sense on this level. No contradiction with materialism.
Reincarnation stories have so far remained unconvincing to me. I have not studied enough of them to authoritatively say they are useless, but I’m sure given enough time my wife (some kind of idealist) will give me all the material I could possibly want to study. If anyone has further comment on this, I’d enjoy discussing it.
Finally, psi has always been just barely out of reach - tantalizingly so. I’ve always wanted there to be psi. Just think how cool it would be to be able to steer your car with the power of your mind, even though you are a quadriplegic. However, I’ve never been convinced that there is anything to it.
Dean Radin wrote a book called The Conscious Universe in which he discusses the scientific evidence for psi, as gathered through meta-analysis of parapsychology research. The most compelling facets of the research were the Ganzfeld and RNGs (random number generators) affected by psi.
The Ganzfeld is a sensory overload type of experiment, the theory being if the senses are deadened with monotonous input the mind will open to psychic imagery. The receiver is placed in a room with red light with half ping-pong balls over his eyes, so his vision useless. The room is filled with white noise to make his hearing useless. Then, he dictates into a microphone the images that come into his mind. Meanwhile, someone else (the sender) is watching a TV and ‘sending’ the images to the receiver. Afterwards, the receiver looks at 4 video clips and picks one as matching his imagery that he gave under the ganzfeld. By chance, he should get 25% correct, but he gets more than that (say, 35% correct.) It’s puzzling, but it’s all a bit too touchy-feely for me to buy into it. I mean, it’s not like the sender is watching Ben Hur and the receiver says “I see Ben Hur”, the receiver says things like “I see wheels spinning and I see giraffes running,” along with about a gazillion other things. Later, when watching the video, the action of horses running is similar to giraffes running, so the guy makes a match. I just can’t get excited about it. In addition, there is an article in the most recent Skeptical Inquirer about new analysis that refutes the claim of statistical significance.
Finally, that brings us to RNG studies. Apparently the data Radin has shows that when someone is concentrating on a random number generator (using true random data from noise in an electronic circuit or other source) the results are ‘less random’. For example, if you do 100 coin-flips per experiment, and do N experiments, you’d expect to get a bell curve of results around 50 heads. When someone is concentrating on the RNG, the distribution changes and you get more events than expected at different standard deviations. The effect is small, but argued to be real. This is the only thing I find exciting unless the reincarnation thing surprises me. How in the world our mind could affect a system like this is beyond me. People like Radin claim that it is evidence against materialism. I’m very interested in it, but I’m not sure that it would be the final nail in the materialism coffin. If this data bears up it will be very exciting indeed.