Embarasssing attempts at drama in a comedy

As a counterpart to the thread Embarrassingly bad “comic relief” in old TV drama I was wondering aboutwhat people’s most memorable attempts at dramatic moments in a comedy are.

The first one that came to mind for me was Saved by The Bell’s attempt at an anti-drug episode where Jessie (Elizabeth Berkley) gets addicted to caffeine pills.

Lol. Caffeine pills?

I’ll go with Family Ties. When the alcoholic uncle comes home storming through the kitchen looking for something to drink and then downs a bottle of vanilla extract bc he couldn’t find anything else.

Played by Tom Hanks. Still, I did like his “It’s 'nilla time!” line before he drank the bottle.

Should we just assume every Very Special Episode has been mentioned?