I also live in central Arkansas. We stopped using Frontline, it just wasn’t working. There are a lot of negative reviews on Amazon, interestingly one review said Frontline did the job when they lived in Chicago, but was worthless when they moved to the deep south.
We’ve had good luck with Advantage 2 for the cats. The dog takes a pill from the vet, unfortunately I don’t remember what it’s called.
I’m glad the dog with a flea allergy is doing better! I hate fleas, I really do.
Fleas reproduce very quickly, so after a few years, only the ones immune to the Frontline medicine will be left. But those can reproduce like crazy, having no competition from other fleas, and being immune to the medication used by owners.
So eventually, specific areas tend to be populated mostly by fleas which are immune to the flea medicine most commonly used by vets & owners in that area. Moving to a different area, you might need to change to a flea medication with a different active ingredient. (Many people think it’s a good idea to switch to a different flea medication every few months anyway.)
It’s a constant battle between the chemists at the medication companies and the power of evolution among the generations of fleas.
Also, flea populations get evolved faster in places where nobody keeps up with flea treatment year round. Let some immune fleas overwinter with all that extra reproducing and soon you have a huge population of fleas that are immune to the topicals and they edge out the non-immune ones pretty fast.
Here is your previous thread.
Moderator Note
Since your previous thread has been found, I have merged the new thread into the old one.
We gave our mini-schnauzer trifexis chewables (spinosad+milbemycin oxime) last year and he had seizures and almost died. Oddly enough our yorkie seemed to tolerate it fairly well, but now my wife refuses to give the schnauzer anything.
YMMV.