I’ve been using Advantage for dogs and am happy with it. Are the products the same and/or equal in your opinion?
Frontline failed our cats miserably this year. It’s worked fine before. I don’t think they’ve changed the formula so I suppose the fleas have changed theirs.
I ordered Advantage this week. I hope we have better luck with this one.
I use advantix for the dog because it’s the only one that’s supposed to repel mosquitoes.
There have been reports in some states (at least according to my dermatology professors), of fleas having acquired resistance to Frontline. It doesn’t seem Advantage/Advantix has that problem (yet). They use Advantage/Advantix to treat cases of flea allergy. As long as there is no associated problems (fleas and allergies), I don’t think they really care about what to use for flea control.
They’re different, the active compound of Frontline is fipronil, and in Advantage/Advantix is imidacloprid. Fipronil distrupts GABA transmitters in the CNS, while imidacloprid disrupts the nicotinic acetylcholine receptors.
There are new players in the market (Promeris), but I have not seen them used, and have little information about them.
Revolution, my friends. A couple years ago, my dog had AWFUL fleas. I think he kept getting them again from the neighbor’s dogs. I’d give him a bath and I’d see them running for high ground. Nothing worked - Frontline, Advantage, flea combing, nothing. I was adopting a cat from the shelter at the time and asked the shelter vet what she suggested for fleas, because I was afraid Dewey was going to catch them from Haplo, and she said I should try Revolution. It killed the hell out of those damned fleas! Seriously, two days later, we were completely flea free. Kinda scary, how well it worked.
That’s funny. I had the opposite experience. Used Revolution, got fleas. Switched to Frontline and viola! Fleas B Gone! I can’t remember exactly, but I think Revolution is more expensive as well.
Different Strokes, I suppose.
Revolution (selamectin) is a big gun… I wonder how it compares to Advantage Multi (which is another big gun, moxidectin). Both are in the Avermectin family… the “will kill almost all pests” family. 
They enhance GABA release, then creating a paralysis in the CNS (and eventual death).
I’m surprised it worked so fast, though. Compared to Advantage/Advantix (same product but with permethrin/pyrethrin added), Revolution is supposed to take more time to work, whereas Advantage is supposed to be a quicker (within 24 hours) kill.
If you want instant kill and seeing fleas jumping to their deaths, try Capstar… Alas, it is also very short lasting (but it is cool to see dead fleas). 
Perhaps they had been cumulatively poisoned. There were definitely a lot of dead fleas and a much happier dog within 24 hours, and as advertised it got rid of the whole flea problem because new ones just died as well.
Frontline works for our dogs and cats. Perhaps we have a different group of fleas in Little Rock than nearby Memphis.
Of course, “nearby” for a Pontiac may not be “nearby” for a flea…
Advantage only kills fleas, not ticks. Frontline is supposed to work on both fleas and ticks. Advantix is supposed to work on fleas, ticks and mosquitos.
Some pests have become resistant to Frontline, unfortunately. My friend cannot use Frontline on her dogs any more because it no longer works on the fleas where she lives. It no longer works on the ticks where we live.
I hate ticks. :mad:
Revolution keeps our dog free of parasites - yes, it costs more, but not wildly more.
Our test is that it keeps her free of ticks and fleas when we visit our friends out in “the country” who have goats, several dogs and whatever random semi-feral cats happen to be wandering by. We might get attacked by bugs, but she doesn’t.
Does it repel, or kill after being bitten? My understand from the 'Dope is that the insect dies after biting the dog.
I just thought I’d pop back in to mention how pleased I was with Advantage.
We applied it last night to all four cats and by this morning there wasn’t a live flea to be found on any of them.
And as long as this is up, I’ll mention that we like Sentinel a LOT.
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It works. She only has fleas on her in the depths of the August Flea Invasion, and they don’t stay, they only appear on her when she comes in from outside, as we have two reinfection sources next door, blast them.
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It’s one pill for heartworm and fleas.
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She eats it out of my hand, doesn’t need it wrapped up in cheese.
Downside: It’s incredibly expensive.
We put up with the cost because…it works.