I’d meant to answer this before, but was on the work laptop.
Yes. I’ve had anxiety for as long as I remember, even as a kid in elementary school. I had my first depressive episode (with a big side of existential angst) when I was in high school.
I was given Prozac in the late 80s (while in college); it helped immensely with no side effects.
My docs and I tried different things when I’d have a depressive episode. A few years later, I took Zoloft. I also tried Buspar for the anxiety, but it made me dizzy. The depression and anxiety got bad a few times because of a very bad boss, or, in one memorable situation, someone going in to a department share drive and changing the work I’d done. It was so freaky that I questioned if it was really happening!
When the migraines became chronic, my docs tried tricyclic antidepressants for both the pain and the depression that comes with chronic head pain. Feckin’ useless. Effexor XR followed; good for depression, useless for my head pain, horrific to taper off.
I went back on Prozac for issues related to perimenopause, also Xanax. Both helped but really, HRT helped more. I love HRT.
I currently take Cymbalta for the chronic pain. We stumbled across it as a good anti-depressant for me after my fiance’ died suddenly in 2011. The psychiatrist I went to see immediately put me on it. When I re-surfaced enough from inside my own pain to notice, I realized that my knee and head pain were reduced as well.
I also use a benzodiazepine as needed. Currently I have a prescription for Ativan, but I’ve used Valium and Xanax, too. I might go through 30 pills in 90s or 120 days, so I don’t seem to have an addictive personality with them.
tl;dr – Yes, several, including SSRIs, SNRIs, tricyclic antidepressants, and anti-anxiety meds.