[QUOTE=Omoikane]
So in my epistemology class our professor is suggesting that we will soon be able to test a certain type of skepticism (that says it may simply be beyond us as a species to grasp the fundamental truths of the Universe) by genetically engineering humans to have bigger brains than is normal.
He suggests that if we double a person’s brain size to 2600-2800 ccs then the resulting person would be much smarter than we are.
From what I remember from Gould and Sagan the correlation between brain size (that is, a brain size : body weight ratio) and intelligence is tenuous at best.
So, what’s the straight dope on this? Is it likely that our modifications would result in a super-human genius?
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I would imagine that bigger brain size at key region may, to a certain extent, increase intelligence but even that’s doubtful. Novel wiring of neurons in the brain may increase a “part” of intelligence like creativity and logic, but even that may not equate to higher intelligence; for example, a child that is blind and suffers from severe autism may develop a mastery of music or art but couldn’t hold a conversation. Depending on your personal philosophy, that child either is an idiot savant or possesses an intelligence beyond the average person.
From what I gather, to increase intelligence, you’d need to change the fundamental circuitry, not wiring, of the brain. Nerves would have to trigger action potentials faster and more efficiently, neurogenesis in the hippocampus would need to occur much faster than it does now (I believe it takes hippocampal neurons about 28 days to go form an undifferentiated form to a full-fledged neuron); you’d also need to sharply increase organelle performance, especially the endoplasmic reticulum, where it has a nearly 80% failure rate in folding proteins into their correct shape. Scientists would need to find every flaw in a neuron and “fix it” and even then you’d still have a problem: where does all of the heat that is being generated come from? In the human body, about 20% of your caloric intake goes to your brain. In human infants, about its about 60% and the heat generated is buffered by fontanels (soft spots) that allows heat to be dissipated easily. If you make super neurons, how much energy will it require and how much heat would it generate? You’d need to make a neuron and all of its proteins heat resistant, otherwise it would just start baking.
This is all (my) speculation. It may be that even with improvements to the actual neurons “human intelligence” would remain fundamentally the same.
This is why its very difficult for me to believe that bigger is better. Sure, you might be able to get an savant but, interestingly enough, many geniuses in history have suffered from mild to severe mental health problems. I don’t have a cite on that but I’m sure I could dig one up.