Using “actors” in the gender neutral sense, of course.
Inspired by the CGI Deadpool test clip voiced by Ryan Reynolds. (And there’s a good example of my standards to call someone a “comedic” actor — despite his work in action movies, I think he’s mostly known for stuff like Two Guys, a Girl, and a Pizza Place and Van Wilder). We know he can have that heroic build, thus probably why he seems like a good casting. Similarly, Chris Pratt was probably cast in the Guardians of the Galaxy film because he’s a redheaded actor with pretty extensive comic experience who also has the heroic build potential.
Lake Bell is unambiguously hot. She could get work as a lead lingerie model, regardless of her acting or comedic talents.
Aubrey Plaza is hot enough for me, but would probably lose out to a lot of other women if she had only ever tried to be a professional lingerie model. Same with Felicia Day, Sarah Silverman, and Alicia Silverstone.
Cameron Diaz, Tia Carrere, and Anne Hathaway have all showed good comedic timing in their comedic roles, though I don’t think they’ve actively sought out a “comedy” title for themselves.