How fast is aspirin, etc supposed to take effect?

Like how long after you ingest it is the drug dispersed?

20 min
Cite? My SIL who is a pharmacist.

YMMV

When I take two aspirin on a full stomach for knee pain, I feel a sense of relief 20 minutes later, by the clock. YMMV.

My understanding has always been (can’t find a cite, sorry) that in general it takes 20 to 30 minutes for any medication that’s swallowed to reach the bloodstream.

Why do you want to know?

While brewha is close enough for most purposes, I might add that pharmacokinetics can vary widely with the patients specifics (age, weight, blood pressure, last meal, etc).

Just curious. I’m remarkably bad at checking this kind of thing. I take the pill and then once the pain goes away, I forget I took it.

My recent experience with severe shoulder pain and Tylenol is…twenty minutes. Let me add that 8 hr, extended release Tylenol for arthritis is amazingly effective for an over-the-counter drug (name brand and generic, both).

To hijack a bit - what about “heavier” drugs like Vicodin?

I always see on TV (especially House) the character is all in pain, lunges for his bottle, pops a pill (without water) and is instantly perky. Is that really how they work?

Half lives

300–650 MG dose: 3.1–3.2hrs
1 G dose: 5 hours
2 G dose: 9 hours

I suspect that might be due to a sense of relief, that they know what is coming.

My experience is also twenty minutes.

I don’t know about Vicodin (it doesn’t work on me), but I get relief from Darvocet within half an hour or so. IV drugs will, of course, work even faster.

With me, most pain killers take 45-50 minutes, and decongestants take about 70-75 minutes.

It depends on lots of stuff, but one thing that varies from person to person is stomach emptying time. Some people’s stomachs empty out in 20 minutes, and some take up to two hours, which greatly affects how quickly things cross over into the bloodstream. Obviously a full/empty stomach matters, too, as does even whether you’re lying down or not!
Apparently, Fundamentals of Toxicology is occasionally relevant.