Ken “The Rattler” Riley
Chuck “Concrete Charlie” Bednarik
Reggie White “The Minister of Defense”
Craig “Ironhead” Heyward
“Prime Time” Deion Sanders
Mark “The Bird” Fidrych
He really seemed like Big Bird of Sesame Street, and his joy and aw shucks attitude were genuine. We need more athletes like The Bird!
Will “The Thrill” Clark
This is a damn good one!
The inspiration for Rocky, Chuck Wepner “The Bayonne Bleeder”
Henderson once said of Steelers QB Terry Bradshaw before Super Bowl XIII that he couldn’t spell “cat” if you spotted him the c and the a.
Sir Arthur “Bomber” Harris.
Pittsburgh Pirate brothers Paul Waner and Lloyd Waner were “Big Poison” and “Little Poison”.
William “what the” F. Buckley.
OK, not his actual nickname. But it would have been the coolest one ever, had it been. 
For a brief time he played alongside another Ed Jones, nicknamed of course “Too Small.” I can’t find him on the Google and don’t remember his height, but everyone was small next to Too Tall.
I remember a James “Too Small” Jones, a running back IIRC, but Google’s similarly coming up empty for me.
I’ll add baseball’s Nick “Tomato Face” Cullop to the list…
Can’t believe no one mentioned Bobby Three Sticks, aka Robert Mueller III
Frank Thomas: The Big Hurt
Doug Gwosdz: Eye Chart
Marc Rzepczynski: Scrabble
Bill Lee: Spaceman
Joe Medwick: Ducky Wucky
Mike Hargrove: The Human Rain Delay
Harry Walker: Harry the Hat
Stan Musial: Stan the Man
Dick Stuart: Dr. Strangeglove
Bob Seeds: Suitcase Seeds
Oscar “The Blade Runner” Pistorius billed himself as The Fastest Man On No Legs.
Teddy Ballgame
Way Back Wasdin
Motorsports has a long history of nicknames for drivers.
Tony “Smoke” Stewart
“The King” Richard Petty
“Awesome Bill” Bill Elliott
“The Intimidator” Dale Earnhardt
“Big Daddy” Don Garlits
“The Snake” Don Prudhomme
Reggie “Mr. October” Jackson
Dave “Mr. May” Winfield (ouch!)
Andre “Bad Moon” Rison
“The Motor City Cobra”, Thomas “The Hitman” Hearns
Almost my favorite Zevon tune
I’m not even a fight fan.
Hurry home early hurry on home
Boom Boom Mancini’s fighting Bobby Chacon
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sitting out the rain