It's in peer-reviewed print: no mental illness "chemical imbalance"

They’ve said it about schizophrenia, they’ve said it about bipolarity, and they’ve said it about depression.

They, of course, being the pharmaceutical industry and the mental health [strikeout]industry[/strikeout] profession. Mental illnesses are, according to them, genuine, specifically known, got-our-scientific-diagnostic-tweezers-on-whats-causing-it, low-level biological brain disturbances, and, to be specific about it. “chemical imbalances”.

Take this pill. You feel the way you do because your neurotransmitters are all fucked up. That kind of thing happens, just like thyroid disease and diabetes, you know. We know all about it, and this pill is, for your ailment, just like insulin is for a diabetic.

Horseshit

We’ve been saying it for years: they’re lying.

(We being the psychiatric inmates’ liberation movement. I’ve been diagnosed manic-dep (before it was renamed bipolar) and paranoid schizophrenic, and have been on the wrong side of the locked doors in a couple of looney bins. But yeah, we’re organized and we’re mad. Well, OK so we’re not all that damn organized, so show me a social-change movement that is?)

Yes, they are lying. Often they have the best of intentions. They want to help. Sometimes they have a bit short of the best of intentions. They want to fill an unmet need and thereby make a profit in the lucrative pharmaceutical arena. Sometimes there’s nothing discernably good about their intentions. They want to render an incarcerated population tractable and amenable to rules, regulations, and institutional control and don’t much care what it does to them in the process. All of these at various times and places, usually in massive parallel.

That which we call mental illness is an aggregated polyglot mess of human emotional cognitive and behavioral patterns that remain identified as such and therefore fall under the auspices of the mental health profession after the easy picks — the phenomena that yielded their etiological and prognostical secrets to conventional scientific inquiry over the last hundred years — were transferred to portions of medical science that both medicine and science regarded as legitimate in ways they weren’t entirely ready to extend to psychiatry. Internal medicine. Endocrinology. Neurology. You no longer get a bed on the mental health ward if you are known to suffer from tertiary syphilis, hypothyroidism, or epilepsy. In the last couple decades of the 20th Century, psychiatry may have mustered enough stature to keep its patients and problems once they are understood — Alzheimer’s hasn’t been fully pulled out from under them even now that we know how it works. But in many ways it’s too late. Most of what’s left in the bag are complex phenomenae that probably don’t have singular causes, physiological causes to which symptoms can be attributed w/o consideration for social and situational factors, and even things which can’t even be unequivocably labeled “undesirable”.

We have been saying this. And in response we often get laughed at, ridiculed, dismissed with “OH, come ON, in this day and age are you REALLY going to try to claim that there’s no such thing as mental illness? C’mon, they know what causes it now!!”

Well now, whaddaya know?! There’s a nice peer-reviewed article reporting research that supports our case!
People who find beneficent effects from psychiatric pharmaceuticals abound; whether the field knows what causes the symptoms we, ourselves, often describe as PROBLEMS or how and why this or that med seems to help alleviate the suffering, that much is still true: some folks benefit from this.

I could also, however, fill a large concert hall with open, out, outspoken, angry survivors of psychiatric treatment we did not benefit from and did not appreciate (yeah, it includes me, I’m in that group).

Many of us were subjected to involuntary treatment. I’d be opposed to involuntary treatment even if they could convincingly prove they had identified a mental illness, knew what caused it and had the cure in their hands. But more to the point, many of us voluntarily turned to them because they said they knew what they were doing, they said they had the fix for the problem, and they were doctors and they were believed, they were listened to and their recommendations followed in good faith.

They lied.

I am not a radical in the movement. I don’t demand that psychiatrists and mental health support staff be disbarred, their professions disbanded, their membership prosecuted for crimes against humanity.

But I think they should be required to come clean about how little they know, how much guesswork they’re still doing on both problem-description and treatment-attempt, and how much is still unexplained and therefore up for grabs to a good explanatory model.

And of course an end to forced treatment, period.

Back to sqvare vun . . . zo, tell me about your mutter . . .

Lifelong depressive checking in. I’ve intuited that “chemical inbalance” is not on the money these forty years. Of course, it IS really “on the money”, because of all the drugs psychiatrists chuck at you - together with a hefty bill.

Interestingly, last time I saw a shrink (he actually had the Wall Street Journal spread across his desk during sessions - honest and up-front, I suppose, if nothing else), I said I didn’t think my depression (about which I am qualified to talk) was fundamentally a chemical in the brain thing. He actually got quite agitated an spent the next 5 minutes or so trying to persuade me I was wrong.

Also, you’re angry.

[sub]Sorry.[/sub]

No, not sorry, just mad and angry :smiley:

Can’t be much help right now, but there’s an article in Nature Reviews Neuroscience within the last year which said that depression was likely due to certain cortical networks not operating in sync, rather than a “chemical imbalance”.

Sorry, Bucko, but that’s not a peer-reviewed research article, it’s an opinion piece in the Essays section of PLoS. Right in the margin at the top of the article it says:

An opinion piece doesn’t carry the same weight as a peer-reviewed research article, sorry. Which is not to say the essay is wrong in its conclusion, but the supporting evidence is lacking. Citing it as peer-reviewed proof of your position is a bit premature.

Ditto.

Well, ten years. :stuck_out_tongue:

You call that a mutter? I’d hate to see what it takes for you to think someone is yelling.
(Yesss, I do know vhat he vas really sayink.)

Hmmph. I see your point. I’m trying to extract their review-policy / standards w/regards to accepted opinion pieces.

Yeah, I don’t know what their standards are with regard to essays–the site doesn’t say explicity. I’ve no doubt there is some degree of critical review and fact-checking, but given that it’s an opinion piece one must take the conclusion with a grain of sodium chloride.

Ah, here’s the PDF, Is Mood Chemistry?

As an added note- just because something gets accepted to a peer-reviewed journal does not mean that it has actually been peer-reviewed. Publication is the beginning of peer review, not the end.

It does on PLoS:

I do not know if the same standards apply to essays published therein, however.

Actually, it typically does. What else would peer reviewed mean, if not ‘given a critical review by peers’ prior to publication? Whether peers review it afterward is pretty arbitrary, and wouldn’t make for very good quality control.

Also, there is nothing in this opinion piece about schizophrenia or bipolar disorder, which are the top two diagnoses of those who are involuntarily treated. I do agree that the term “mental illness” is extremely broad and is sometimes used in lieu of finding out the real causes of the disorders, sort of shoving them into a highly disparate category where they fester in ignominy. I would love to see those two diseases (and others) recategorized as neurological disorders. Would do a lot for credibility, you know. I am also opposed to involuntary treatment for the same reason I don’t think people should have to have chemotherapy if they don’t want to or amputate a diseased limb if they’d rather not–personal choice. Sometimes you have to detain people for their own good and the good of others (that goes for non-MI people as well), but I agree that it goes too far.

But yeah you didn’t pick the best cite to support your case.

There is usually a different level of review to determine whether something is merely publishable than the more serious and widespread review which occurs afterward. The first level determines whether something is worth calling the scientific community’s attention to. the second phase is the one that counts. Michael Behe has gotten himself past the first level once or twice but gotten his ass handed to him after publication.

I work as a research assistant in a hospital, and I can vouch that this is right. It depends on the publication, though; more respected publications do not print articles until they are fully reviewed and passed all levels. My boss explained the whole thing to me. But since this is an editorial I don’t know what its process is.

Bipolar patient and former behavioral neuroscience Ph.D. student checking in:

You have an agenda to prove and it is not only scientifically unsound and unlearned, but also dangerous.

The brain is an organ like any other. Do you think it can’t develop any problems? Do you think it is just antenna picking up the soul from afar?

Do you really want to debate proven changes like in Alzheimer’s disease, strokes, and physical or drug induced brain damage brought on by many causes against parallel symptoms with mental illnesses.

Lithium literally saved my life 2 years ago. It wasn’t psychological. I was on several other drugs and then no drugs right before that. The change was so profound that family members cried when they saw me before and after. That is an element. It isn’t a drug that the pharmaceutical industry makes money on.

Do you really not believe schizophrenics when they say they hear voices? Have you never seen a Bipolar person manic beyond belief? Those aren’t exactly rare things. No one would choose that and I certainly didn’t.

The symptoms cluster quite well. I can walk into a psychiatric ward of your choice and give a diagnoses for most of the people in there after talking with them for just a few minutes.

Your attitude is offensive and extremely dangerous to those who will hesitate to get treatment because of attitudes like yours.

Exactly. Getting your data/theory published in one journal is just the very beginning of the process. No doubt there are countless other papers showing that “chemical imbalances” are real. And it’s entirely possible that mental disorders have multiple causes. I think the OP is getting a bit carried away. And unfortunately (for people like the OP), it’s rare indeed for a reigning theory to be overturned by one paper. I’d expect that something like this would take at leat a decade for a new paradigm to emerge.