Last letter = First Letter, min 3 syllable word chain

senator

Re-Animator

robusto

ornamental

lyricist

Tracheotomy

yesterweek

Keokuk

Kokanee

epinephrine

elephantiasis

Sisyfus

sassafras

Supercalifragilistic

coriander

Reintroducing

guttural

loquacious

sociable

Erasmus