Let's come up with some all-too-pertinent honorifics

For reference see Honorific - Wikipedia

As an example consider:

Your Irreverence, Lenny Bruce
Your Flatulence, Ted Cruz
Your Irrelevance, Pauly Shore

John Boehner - Your Stubborness
Alabama Supreme Court Chief Justice Roy Moore - Your Intolerance
Anne Coulter - Your Ignorance
Justin Bieber - Your Insolence
Jimmy Fallon - Your Irreverence

I think all of these are probably interchangeable.

Your Highness, Cheech Marin

Good ones, folks! Thanks for the additions.

I’d go with “Your Orangeness” for Boehner.

And “Your Tortoiseness” for Mitch McConnell.

For Mitch I could see:
Your Oiliness or
Your Greasiness or even
Your Sliminess

Your Insolvency, Nicolas Cage