From computer games set in the past up to the present. What is the most powerful man-made (non alien technology) weapon?
No biological weapons allowed cos that’s too messy.
Metal gear Rex? Banana bomb? Yoga flame?
Define “non-future”. Command and Conquer: Red Alert was set at the time of WWII, but in an alternate timeline where Hitler was killed before the whole Third Reich business. So are we allowed to count Tesla coils and the Chronosphere?
Alternately, what about fantasy games? Is magic allowed, or just technology?
In any event, though, there are plenty of games which have nukes (including the afore-mentioned C&C:RA). So we’ve got to start there.
I see what you mean about magic. Ok no magic. No alternate timelines. Aw fuck it.
It’s a stupid question. Mods please delete.
No wait, yes to magic and yes to alt realities.
Gotta be man- made though, so no banana bombs after all.
I should have read the op before posting.
And it has to be before the year 2012, our time.
The PATRIOT gun from the Metal Gear Solid series. Armor-piercing bullets and unlimited ammunition because, y’know, the drum was shaped like an infinity symbol.
CODEC call:
Sigint: From the looks of it, it’s fitted with a 100-round drum magazine… and it never runs out of ammo?
Naked Snake: Never.
Sigint: Why’s that?
Naked Snake: Because the internal feed mechanism is shaped like an infinity symbol.
Sigint: Ah, I get it. Yep, that’ll give you unlimited ammo.
Alternative timelines I’d go with the mini-nukes from the Fallout universe…the nastiest being the MIRV from Fallout 3, which it was death to use (at least I died the 2 times I attempted to use the thing). Man portable nukes are always going to trump just about anything out there. 
-XT
I’d say the nukes from CIV (whatever).
Though technically, isn’t STAR WARS set long, long ago?
That’s way in the future.
Any game with ICBMs. Plenty of them out there.
Well, it’s an alternative time line…not sure how far in the future it was. What about Doom? When did that supposedly take place? There is always the BFG. 
-XT
Fallout 3 is like 2270 or something.
Gordon Freeman’s crowbar.
Fallout 3 is in 2270s but all the weapons (except the things you build like dart guns out of toy cars) are from the 2070s at the latest. So I guess still doesn’t count
Yeah, but the MIRV is a pre-war weapon. But the war was 2077, so still disqualified I believe.
This was going to be my answer, and when someone inevitably complains about it being set in the future I was going to retort that when they get to the Borealis in Episode Three, they’re transported back to the 60’s and have to elude the minions of Cave Johnson. 
MIRVs do exist now, though. And if you’re going to disqualify Fallout, they still show up in Scorched Earth, which isn’t set in any particular time.
Of course, as Scorch weapons go, they’re pretty weak. What you really want to go with there is a Death’s Head.
The nuke in civilization revolution is much stronger than nukes from other civ games. It actually DESTROYS the city.
Yes, but it is also in a galaxy far, far away. And the OP said no alien tech.
And to get nit-picky it was only a long time, not a long, long time.
The humans in Star Wars were, as far as we know, humans.
I’m thinking an argument for The Death Star is viable here.
Humans they may be, but they’re not Terrans. And thus, aliens.
Now that’s just silly. In reality, the magazine has to be shaped like a Möbius strip in order to have unlimited ammunition.