Many fictional characters in the last 60-70 years, be it a superhero, supervillain, monster, or something else are often the result of some kind of nuclear accident, testing, bombing, waste, etc.
Captain Atom
Sun Boy (powers granted by an accident with a power generator)
Socialist Red Guardsman (Not sure how he GOT his powers, but he is radioactive because of them)
Cyclotron, and by extension Al ‘Atom’ Pratt, and Albert Rothstein (AKA Nuklon, and Atom-Smasher) - Al being an enemy of Cyclotron, who gained superpowers from dealing with him regularly, and Albert being Cyclotron’s grandson.
At least one of Iron Man’s suits of armor was powered by a small nuclear reactor.
Lex Luthor got cancer from prolonged exposure to radiation from the kryptonite ring that he wore.
She-Hulk received a transfusion of Bruce Banner’s radioactive blood.
The first Spider-Woman’s first origin story had her getting radiation poisoning as a child, with the resultant attempt to cure her resulting in her development.