V’s a primary spellcaster, who has been focusing entirely on the idea that magic will win the day. So I’m going to guess the answer is “No.”
How many HP does Xykon have? Say he’s 25th level, 7 HP per level - no Con because he’s Undead - so about 175 HP. O-Chul does 1d4 + Str x2 + Power Attack, x2 on a critical (improvised weapon) and is probably about 15th level - he can’t manifest a Holy Weapon. Call it a max of 46 on a full-effort Power Attack with confirmed critical. So O-Chul can’t one-shot Xykon through damage alone, nor can he do enough damage to force a save vs massive damage.
O-Chul seems to have taken two hits from the Meteor Swarm, so that’s 56 HP damage. I’m assuming his Evasion ability (from his Monk levels) enabled him to avoid the rest. He obviously failed on the Lightning Bolt, so took 60 HP there (save for half damage failed). So he’s taken 116 HP damage. At his level, he’s likely got much more HP than that. Say Con 16 for 9 HP per level gives him 135 HP. He’s seriously down, but not out.
Undead are immune to criticals. And massive damage.
Well, that’s about how many he started with, anyway. He’s not at full HP at this point, after V hit him with sunburst and crushing hand.
A couple of points:
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Undead aren’t subject to critical hits.
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IIRC, they aren’t subject to the “death by massive damage” rule, either.
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O-Chul could, in theory, cast bless weapon on his improvised weapon (it doesn’t require a material component or focus), which would be enough to bypass Xykon’s damage resistance (liches have DR 15 / bludgeoning and magic), if he uses the blunt end of his jail-cell bar.
The way Evasion works, if you make a Reflex saving throw, you take no damage, but if you miss the save, you take full damage. You’d need the Improved Evasion ability to take reduced damage on a failed save; Monks don’t get that ability until 9th level, and I wonder if O-Chul has that many levels in Monk. 
O-Chul doesn’t have monk levels-- You’re thinking of She-who-must-not-be-named, there. O-Chul is a fighter/paladin. He just survives because he’s got a metric ton of HP.
Does O-Chul have levels in monk? I thought that was Miko.
Y’all need to factor in that O-Chul got hit by Disintegrate, as well, before Redcloak took off.
That’s a paltry 5d6 damage if O-Chul made his save.
I’m not sure where Giant is going with this, but V is seriously stuck. Remember, they can’t Teleport any more, that being a spell in one of their banned schools. Access via the Splice has ended.
Phylacteries are tough. They may look frail, but the magic that creates the phylactery makes it as hard as adamantium (ie Hardness 20) and it has a surprisingly large number of hp. I honestly doubt whether O-Chul’s improvised weapon even scratched the thing.
No, the one hope there is for V to Disintegrate it, before it gets picked up.
He’s sacrificing himself. For who’s benefit, I’m not sure yet.
Yeah. Remember that O-Chul is basically a hopeless case at this point. Get used to the idea that he is going to die while attempting to do something very noble. He’s not getting out of this alive.
He will not be able to destroy the phylactery. My highest hope is that his sacrifice will pull V back away from the Evil persuasion.
I believe someone else has already raised the possibility of throwing it into the Rift. I don’t care how many epic abjurations Xykon’s stuck on that thing, it ain’t standing up to the Snarl.
That’s my second highest hope. My highest hope is that his example will be what later causes CITD to switch sides.
Right. Yes. That too. Good is often more insidious than Evil, eh? 
There’s something I don’t quite get, here. Why do the fiends say “if the elf dies there, it’ll all have been a gigantic waste of time” ? The splice is over, isn’t it ? They’re not getting anything anymore (unless their endgame never was the ownership of V’s soul postmortem, of course, but then I fail to see what else it’d be). Or are they hoping the elf will make it so they can offer him/her another better, stronger, faster splice for 10x the price, crack dealer style ?
It’s never been about owning his soul postmortem. The deal was that he would have to serve them, while still alive, for as long as the splice lasted. Some time in the future they will call on him to repay the debt, while still alive.
See the terms of the deal here. They don’t want eternal dominion of his soul when he dies, that wouldn’t be fair. He maintained the splice for about 22 minutes, so each fiend can call on him for 22 minutes of service at a later date.
edit: to be exact, they “get his soul” for a time equal to the length of the splice. Many people interpret that to mean that he will have to perform some service.
Their cost for the splice was that they can take over V at a time of their choosing for a time equal to the duration of the splice. If V dies now they can’t collect on that. V’s immortal soul is, if i recall correctly, still his/hers.
Re: the fiends and the “waste of time.”
Spoiler just in case:
As mentioned on the Giant’s forums, we know that Redcloak’s plan is to use the threat of the Snarl to blackmail the divine powers into giving NPC races a level playing field.
More than likely, the fiends want to do the same… except going further and actually wiping out the good pantheons outright, leaving them the only divine/near-divine game in town.
Hmmm. I interpreted it as “limited duration damnation in each our Hells” myself, like Faust : The Demo Version if you will. If V doesn’t have to die for his soul to be in some fiend’s hands, that does open some not-very-nice options down the line…
Or, wiping out ALL the gods, good and evil. It’s mentioned here that the Snarl is therorized by some to be more deadly to gods than mere mortals. Or possibly, fiends as well ?
They may even want to do a repeat of history, and let the Snarl destroy the world and then remake it. This time, with the fiends, and the fiends alone in charge of the design.
I think that yours is the same interpretation that Vaarsuvius made – that s/he’d be in for some torture time in the lower planes after death, a price V was willing to pay to save Kyrie and the kids. But yeah, this is indeed a false assumption on V’s part, because as Qarr notes, the fiends wouldn’t have done so much research on the wizard for a standard soul-torturing post-mortem. They could’ve accepted Kubota’s application if that were all they cared about. No, they want V. specifically, and presumably it’s got something to do with the gates – I believe it’s been mentioned that there’s a need for an arcane caster (in addition to a divine one) in order for all this to go down.
Jeez – in taking a second look at the strip, I just realized how frighteningly close Xykon is to that door (and by extension, Vaarsuvius)! You can see the door right by Xykon in the eighth panel, and in that final panel, V. is only a couple of feet from Jirix’s body. Yipe!!! Scary.