(I have a high school level understanding of biology and grade school understanding of chemistry, so please be kind)
At Gov. DeSantis’s latest press conference a man from Gainesville said,
The vaccine changes your RNA so for me, that’s a problem
My understanding of RNA is that it is like a message from the nucleus of a cell to the organelles that make proteins. I think of it like me/the nucleus writing “make me X protein, please” on a piece of paper, folding it up into an airplane, and tossing it to the protein-making organelle. The “paper” medium, and therefore my instructions, are RNA.
And my understanding of the RNA vaccines (Pfizer & Moderna) is that they deliver strands of ready-made RNA so the organelle can make proteins that will trigger an immune response. So that would be the nurse/EMT tossing her own paper airplane message (“make some spike proteins please”) to my ribosome. She isn’t actually changing any messages I’ve sent, but she is changing my instructions. I might have requisitioned three X proteins and five Y proteins, and now I’m getting three X proteins, some spike proteins, and five Y proteins.
I don’t know why Gainesville guy has a problem with that, but it does kind of make sense to me to say the vaccine ‘changes your RNA’. It’s changing my messaging.
Every news report I have read implies that I misunderstand something. For example, this is from Orlando-6 which rated Gainesville guy’s claim “not true”:
News 6 brought that claim to University of South Florida Epidemiologist Dr. Jason Salemi and Pediatric Pulmonologist Dr. Akinyemi Ajayi who both agree, it’s just not true.
“A lot of people are saying, ‘I’m not getting the vaccine because it will alter my DNA and RNA.’ No, the mRNA breaks down quickly after entering people’s cells and is unable to alter your DNA,” said Salemi.
“it doesn’t change it at all. The interesting thing about the vaccine is all it does is injecting you with a recipe that teaches your body how to create an antibody. The moment your body creates the antibody, the first thing it does is it destroys the recipe. It doesn’t enter the nucleus,” said Ajayi.
RNA also lives in the nucleus and is unaffected by the vaccine, according to Ajayi.
I don’t know if those scientists were presented with the specific question of whether RNA vaccines change your RNA. When Dr. Ajayi says RNA lives in the nucleus that really confuses me - if RNA is only found in the nucleus and RNA from vaccines break down without ever breaching the nucleus (per CDC) how does the vaccine even work? I clearly misunderstand something important here.
~Max