Please share your experiences with buproprion (Wellbutrin)

In My Humble Opinion
1

Today I started a buproprion regimen. I took my first pill about 90 minutes ago and so far, I don’t feel any different… maybe just a little bit more anxious than usual.

Would you please share with me your experiences taking buproprion for the first time? Thanks.

2

Antidepressants take a lot longer than 90 minutes to kick in. Try 2 weeks.

2 weeks into my trial run, I got more depressed, so I stopped taking it.

3

This isn’t true, it takes 2 weeks for efficiency but effects from bupropion start within an hour. It’s a mild cathinone stimulant, pretty jittery when you first start it.

I personally found bupropion pretty efficient in treating depression, but I started getting hypomania so I stopped antidepressants all together.

4

Efficiency? Do you mean efficacy?

Most clients I have talked to notice only very mild side effects in the beginning, usually mild nausea. OP, don’t expect much for a couple of weeks.

5

Took one pill. Got a nasty hives-like rash on my butt. Made a fast trip to the drug store for some anti-itch spray. The end.

6

I’ve been on it for several years. It’s never made me particularly jittery. When I first started, I went through a period where I had trouble finding words. My mind would just go blank on a word I knew that I knew. That eventually went away.

The weirdest side effect I had was when I bumped up to 450 mg. from 300 mg. I was driving my usual route to work one morning and realized I did not have a clue where I was. It was a very fleeting disorientation, but it freaked me right out. Fortunately, that was the only time I experienced that.

Other than those two little hitches, it works great for me. I’m now on 150 mg. with 20 mg. of Celexa.

7

Yeah that’s what I meant, I guess I’m just sensitive to any stimulating medicine cause I always got jittery starting bupropion.

8

Worked well for many years except it made my insomnia much worse (but I’ll still take that over the side effects from SSRIs), mostly just when I first started taking it or would increase the dosage. I stopped taking it after getting serotonin syndrome, but that wasn’t really the drug’s fault so I don’t hold that against it.

9

I never had any side effects, it helped with my depression, and it may have played a part in my quitting smoking. So it gets a triple thumbs up from me.

Good luck.

10

Are you trying to quit smoking? Improve your mood? Or, other?

11

Thought it was awesome - it counteracted my depression plus I got my sex drive back in the process. No side effects that I could tell.

12

Three hours later and I still feel no different.

13

I took it to help quit smoking. No idea how much. I don’t remember how it made me feel, think or sleep. I just remember these 2 things:

  1. It made cigarette smoke smell awful to me. AWFUL. Two other people in my house smoked still so I had to sit around with my nose next to a fragrant candle.
  2. I had been prone to panic attacks previous to taking it, and while I was on it I had the worst, most scary, face-slapping, hair-pulling, car-smashing panic attack in my life (I was in my car on the freeway and had to pull over to call my brother to pick me up). I almost beat the shit out of myself and my car.

That was the end of Wellbutrin for me.

14

Mrs. Homie smoked some cannabis while on Wellbutrin and the results were… undesirable. She is now off cannabis. YMMV

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15

I took it for a couple weeks as a quit-smoking aid. It deadened my taste buds, but there was no other effect. I don’t recall the dosage.

16

I’ve been on it for about 5 years and have found it helpful in controlling my depression. The only side effect I experienced was that I started to sweat a bit more and had to change to a stronger deodorant.

17

I took it for a couple of months. I became more assertive, which I liked. Then I became aggressive and fought with the boyfriend a lot. He left, and I became progressively shakier and more agitated. I wasn’t sure the Wellbutrin was causing this, and the prescribing physician took his sweet time about calling me back. It got so bad that I was ready to go to the emergency room. I stopped taking it and calmed down after a couple of hours.

My father takes it and says it gives him bad dreams, but he takes a lot of medications, so it may not be the Wellbutrin.

18

Many years ago, i took it to try and quit smoking. I dont remember the dosage. It made me ANGRY. I ended up smoking more just to try not to lash out at everyone who looked at me. I didnt last long on it.

19

I haven’t taken it, but my teenaged son did, briefly, for Depression. He said it did help with his feeling sad, some, but it made him feel very angry. He started cutting. We stopped the Wellbutrin, and he’s refused to try anything else. (He also stopped cutting, thank goodness.)

20

I’ve taken a number of meds, and their side-effects tend to get me after awhile. But I don’t have any complaints about Wellbutrin.

Two side effects that I KNOW Wellbutrin caused: vivid dreams and an “electric” shock sensation in my ears. Both temporary.

I suspect that Wellbutrin made me lose my appetite for a few months a couple of years ago. I lost some weight (it will do that to many people). It’s easy to shrug off no-appetite like it’s no big thing since there are worse things that can happen to you. But it truly did suck while I was experiencing it. So be careful.

There is a difference between XL and SR, by the way. I was on SR for a long time but my mood wouldn’t budge from “meh”. I wasn’t ready to take a header off a bridge and if you had asked me, I would have told you I was fine. But I couldn’t get excited about anything either, and I knew that was not good. When I was switched to XL, suddenly the world seemed a lot brighter.