The current version of the game is multi-player only - programming the computer to play this new kind of game is rather hard, but something we hope to do someday.
As for strategy, the same fundamentals apply as in any strategy game, but quantum games ad a new twist which I will get to later. First, there is the standard interplay of offensive and defense. In both versions of tic-tac-toe (classical and quantum) the 2nd player (O) has to emphasize defense over offense. This is the same situation in chess, where black (who moves second) also has to emphasize defense over offense, but to a much less degree since chess is longer and more complicated.
Second, is any move which forces the opponent to make a particular response. Ideally, this limits the opponent to just one choice, but even reducing their viable options to just a few moves helps you to keep the initiative. The simple force is a move which if the opponent does not respond immediately allows you to win on the very next move. Finding situations that correspond to a force move lead one to study the end games, nearly complete games with only a few moves left to go.
Third, the fork. This is basically two force moves at once. The opponent can only respond to one, and so an immediate win is guaranteed.
More advanced versions of the force and the fork simply look more than one move ahead.
Now the strategy that is unique to quantum games - this is the cool part. About half-way through the game start looking less at the quantum board than at the set of classical boards it represents. This set is called the classical ensemble, it is shown underneath the quantum board and can consist of as many as 27 simultaneous classical games. These are all the possible “realities” implied by the quantum game in progress. When you make a quantum move it duplicates the classical ensemble, each move of the spooky pair is made in one of the copies, so after a quantum move there are more classical games in the ensemble.
However, when the quantum move entangles with existing moves, or even more dramatically, when it cross entangles existing entanglements, many of the new classical games are not legal. The computer doesn’t even show these. This means that after an entanglement move, there may be fewer classical games. The missing games represent histories that have been erased from existence. Refer to any science fiction story about time travel. So here is the ultimate strategy in quantum games, find the moves that erase all the realities that benefited your opponent.
Put succinctly - attack your opponent’s past.