Stupid and Contagious by Caprice Crane. Unfortunately, the synopsis is very short. I can tell you that I adored this book, and after I read it, Kim Gruenenfelder popped up in my list of Amazon recommendations, and there are some similarities in their writing styles.
I’ll second this one. Well, the book part – I didn’t enjoy the movie. Eat, Pray, Love didn’t get the greatest reviews, but the fact that it was on the NYT bestseller list for 199 weeks and made into a movie should give you some idea of just how bad it ISN’T. Though the book is popular enough that I wonder if your wife has read it already.
While I love the show, I haven’t been able to interest DrMrsB in it.
Although my parents have the books so I’m planning to swipe them at some point in the future