Drea De Mateo
Chrissie Hyndes of the Pretenders…love that black eyeliner.
She’s who I came in here to post. So I’ll say it again. Allison Janney.
Felicity Huffman (at least from Sports Night; I’ve never seen Desperate Housewives).
Don’t forget Allison Janney.
I’ll go along with that. I think she is smokin’ hot, but not quite in the category of the women in the other thread.
Also on my list, Lori Petty. Tank Girl only clinched it for me, but she struck a chord the first time I saw her.
Allyson Hannigan. I know some don’t find her sexy. I feel sorry for those people.
Alicia Silverstone. mmmmm, women who pout, hmmm, hmmmm.
For singers, Joan Jett and Lita Ford were my first ‘celebrity’ crushes when I was a teenager. Give me the chance today, I’d still give it a go.
Lindsey Lohan.
Oh, and Anna Paquin. Hubba hubba!
The French have a name for it, of course (French has as many words for female allure as Eskimo has for snow): jolie laide. Yes, I said jolie. 
But Americans who don’t know French will look at jolie laide and read “jolly laid,” thinking, that sounds more English than French. —How was the date last night, old chap? —Jolly laid!
In French it’s pronounced zho-lee led. As in Zeppelin.
I’ll mention Ileana Douglas again because she was the first one I thought of when I saw the title of this thread. Also, she deserves credit for not yielding to the temptation to get a nose job which, arguably, could’ve helped her land more conventional “leading lady” roles.
Still, I think all the women mentioned in this thread are certainly not ugly by any means. You may not think they’re “beautiful” in the mainstream mass-media sense but they’re all quite physically attractive in their own way.
Ellen Barkin in Sea of Love.
Ellen Barkin in The Big Easy
Holy Moley Smoking Hot!
She plays Julia in Nip/Tuck. Not too pretty in the face but overall definitely sexy as hell.
You’re kidding, right? In what universe is Miss Piggy not beautiful?
Good body + not-so-beautiful face (or at least not Hollywood beautiful) = sexy but not beautiful.
just one point of difference: i think allison janney is drop dead gorgeous
Nena, of 99 Luftballon fame!
I had a huge crush on her as a teenager. She makes me Bockgeil!
I’d be Jolly Laid with a 1970-era Karen Black.
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Controversial choice? Not quite beautiful? Absolutely incredible pair ‘o’ gams? Yes.
Tilda Swinton.
Ohhhh, good choice. I fell madly in lust with her after her role as Gabriel in Constantine. Which is funny though because I first thought she was a really effiminate male.
Marcia Gaye Harden
OK I can’t let this go on any longer. I don’t see why this should be confind to females. I don’t have to start another thread do I? I mean it seems bisexual enough…
So therefore
Wilim Defoe
Jeff Goldblum
Steve Buchemi
Iggy Pop
Of course I think all those guys are in fact beautiful but probably only according to me. And yes I like wide expressive mouths and large eyes…does seem to be a trend there. Guess I’ve learned something about myself today.