Well, if it helps, I moved up here in late 2004 because I got a job. I have since resigned from that job, changed careers, gone back to school, gone through a handful of other jobs in my new field (including two right now), and reinvented my entire life. I love it here – I live in Casselberry, but I mean Orlando as a whole. I was miserable in Miami (where I was born and raised, and moved back to after my first two degrees), and never fit in down there. I think someone the OP’s age, with her interests, can definitely carve out a niche for herself, make a decent living, and have fun around here.
As for apartments, a lot of the affordable places once aimed at students are converting to condos, which is not a comforting trend. I would look around the UCF area, maybe out east by Waterford Lakes, maybe around the University Blvd./Goldenrod Rd. area. A lot of the student-focused apartment complexes offer multi-bedroom apartments with individual leases (so you wouldn’t be responsible for flaky roommates being late with rent and the like), but you may not want to deal with roommates at all, especially not college students. I second the idea of getting a job first, and then trying to move somewhere reasonably close.
The traffic CAN suck, but being from South Florida, I scoff when people complain about the rush hour gridlock on I-4. I commute on I-4 every day, and it is NOTHING compared to the Palmetto Expressway, the 836, I-95, and even suburban streets like North Kendall Drive in Miami, which turn into literal parking lots every afternoon like clockwork. I-4 is very convenient for me, but you may find yourself having to take the major toll roads, the 417 (Greenway) and the 408 (East-West Expressway). Get yourself a SunPass for your car so you can zip through the tolls and have them bill you automatically, rather than having to wait in lines and always worry about having enough money on you.
As everyone has said, there are LOTS of service jobs to be had, and not just in the southern, touristy parts of town. The best venues for live music are the Hard Rock Live at Universal Citiwalk and the House of Blues at Downtown Disney, which both host national acts. I love them because they are non-smoking venues, but YMMV. As someone else said, the Social is the best live music club in downtown Orlando, which isn’t that great otherwise. I hate the club scene, though.
If you need any other recommendations – restaurants, bars, comic book stores, anything at all – let me know. I’m not a native Orlandoan, but perhaps I can offer a semi-newcomer’s perspective you’d find just as useful (especially since I’m still – barely – in my 20s). Since I travel so much for work, I have gotten to know several different areas of the city.