I’m a Cal alumna, and my sister is currently a senior there. I loved Berkeley my undergrad experience for all of the challenges I encountered, for the diversity, and for all the different opportunities and programs. I took a couple of “for non-majors” neurobio classes and loved them. Yes, you get kicked out of the dorms after your freshman year (unless you come back as an RA) but why would you want to live in the dorms more than one year? They’re expensive, you have no privacy, and generally only freshmen live there!
Berkeley has the advantage of having one of the best student-run cooperative systems in the country, with (IIRC) 19 houses and 3 apartment complexes. After the dorms, I moved into the co-ops and loved it there. They’re much less expensive than either private housing or dorms, and food is included if you live in one of the houses. Co-op link
There will be plenty of opportunity to interact with professors, if you initiate it yourself. Because of class size and other constraints, professors are generally very busy people. However, in my experience, not one professor was against the idea of student interaction. They all have office hours. Right now, my sister is involved in a research project with a psychology professor that is basically her dream project. She got the position by getting to know the professor in office hours.
Berkeley will be a challenge. Your friends may not have huge workloads, but I guarantee you that they are not the smartest or hardest-working people in their classes, and their grades may not be what they expect! I found it to be an incredibly intelligent and interesting environment, and if you feel you are up to the challenge of Chem 1A first semester freshman year with 1500 other students, one professor, and a history of half the class failing, then by all means take that challenge on. I did it, thinking I was going to be a bio major, and I got a C in that class. The only C I’ve ever gotten in my whole life. If I hadn’t had several other challenging classes at the same time, I might have done better in the class. That one, along with several others you will take as a neurobio major, will be a weeder class - so many people at Cal start out pre-med, they have to weed people out early. It definitely wasn’t the best class I’ve ever taken (in fact, it kicked my ass), but for the first time in my life I had to WORK HARD to understand something. It was a great feeling.
I didn’t end up being a bio major. I designed my own major (another program Berkeley has), got to take all the classes I was interested in without having to take classes I didn’t want to take, wrote an honors undergraduate thesis, and thoroughly enjoyed my experience there. It was a great way to get an education that I wanted, and not be just another number. I highly recommend Berkeley as an undergraduate school if you can get in.
How about Harvey Mudd or any of the other Claremont colleges? Or did you want to go far away from home?