Q - yeah
Second Mr. Burns there
And my fav one of all time, well perhaps not from movies, but close enough, Gollum from the Lord of the Ring trilogy
Yes, my preciousssss 
Rimmer from Red Dwarf, Q from ST:TNG, and Ernest T. Bass from the Andy Griffith Show.
Another vote for Dick Dastardley here.
And for Mr. Burns.
Does Sylvester count? I’m sure Tweety Pie thinks so!
And the ultimate, all-time champion, cartoon villain that meets ever single criterion -Wile E. Coyote.
Alex Krycek
Tunguska/Terma (!!!)
Anasazi/The Blessing Way/Paper Clip
Piper Mari/Apocrypha
Patient X/The Red and the Black
The End
Two Fathers/One Son
Mmmmmmmmm…