Kat Richardson’s Greywalker novels are entertaining. Sure, she has love interests, but to no greater extent than Harry Dresden does. They’re supernatural gumshoe books.
A lot of De Lint’s early stuff was very good, but apparently an acquired taste.
Elizabeth Ann Scarborough’s Godmother series is very readable Urban Fantasy though not exactly deep.
Try Simon Green’s Nightside series, and also his Secret History series.
Christopher Moore? Humor fantasy.
Thanks for starting this thread, jsgoddess.
…although I’ve read most of the authors mentioned here already.
I’ll be another voice for Charles de Lint- sure, he’s a bit la la new-agey, but he’s readable. I think he may have been one of the first people to use the term “urban fantasy”- before it became the werewolf sex genre.
I’ll second Christopher Moore, particularly A Dirty Job
Seconding the Felix Castor novels. If you like Dresden, you’ll probably like these. I too only read a few Dresden novels, but from what I’ve read, I like Mike Carey’s work better. (Not that Butcher is bad, just not as good as Carey.) It’s the same idea: noir plotting grafted onto a supernatural world.
I really like Christopher Moore as well, but the tone is just miles away from stuff like Felix Castor and Diana Tregarde.
IMHO, the series went way off the rails after book three, and it’s kind of a genre of its own, but Stephen King’s Dark Tower series has elements of urban fantasy - especially The Drawing of the Three.
Sergei Lukyanenko’s Watch series is pretty good.
Glen Cook’s Garrent PI series might fit the bill.
I was going to suggest the Garrent PI and Nightside series, but someone has beat me to them.
There’s the Hollows series. While the love life of the main character plays a part of the story, it isn’t the main story. It’s set in an alternate universe where everything from the 1950s onward was changed when the discovery that witches, werewolves, vampires, etc are real.
In regards to the Nightside series mentioned earlier, there’s the Forest Kingdom series. It’s sort of a prequel to the Nightside, though they have little in common. (Namely the Street of the Gods, and some of the immortal beings.)
Two offbeat recommendations that I’ve seen very little love for:
Sandman Slim. I was unimpressed by this book at first: it felt like a Jim Butcher by way of Quentin Tarantino knockoff that was just trying too hard. By about a hundred pages in, though, I was in the swing of things and was absolutely enjoying the silly, over-the-top profanity and violence coupled with a hypermacho jokey protagonist. It still seemed like a Jim Butcher knockoff, but I had a helluva lot of fun with it.
Sharp Teeth. It had interesting reviews, so I checked it out of the library. It began with a page of prose poetry, which seemed like Hard Work to me during the school year, so I flipped a page–and saw more prose poetry–and flipped more pages…the whole book is one long prose poem.
And it’s flippin’ AWESOME.
The idea of an epic poem about werewolf gangs in southern California just doesn’t sound to me like it’d work. But oh, it worked so well for me. The prose poem format manages to add a gritty, almost film noir feel to the whole shebang, a bit like how Cormac McCarthy’s disdain for punctuation makes his books feel stark and cowboyish. The story is complex and interesting, and the characters are compelling.
For me he was the opposite. I really enjoyed his books at first, but the more I read of them, the less convinced I was that he knew what real people were like. Something about them just doesn’t sit right with me at all. He seems like he’d be a great guy in person, but I have no desire to read any more of his books.
Because of a recommendation on this board, I read those and they are very good. It took me a while to get into them, but it was worth the effort.
I was going to recommend those, but I have a feeling the OP will find them too much like she was looking to avoid, as there’s a LOT of romance in those.
**jsgoddess, **I *so *agree! As a 48 year old male who is a big consumer of urban fantasy, I still often stop and think: Man, I am *really *not the target audience. Still, it is mindless entertainment and I usually just flip past the non-sense.
Most of what I would recommend has been mentioned, and some that has been mentioned I could not recommend…
Yeah, I read the first one and gave it three stars on Goodreads, then bailed partway into the second. The relationship between the main character and the vampire woman was like battered woman syndrome. Really creepy.
I’ve read many of the authors mentioned, including Mike Carey (like very much), Charles DeLint (so-so), and Simon Green (do you know how many times he wrote “in the Nightside” in the first book of the Nightside? Neither do I, but it had to have been a MILLION AND A HALF). 
But there are definitely some new names to me and a couple of names I had in my to-read list that I’m bumping up to the top.
I think the more recent Dresden books are better than the Mike Carey books I’ve read (I haven’t read the 4th one yet. Not at my library for some reason). But the Carey books are extremely enjoyable for me.
There are four Felix Castor books? There’s The Devil You Know, Vicious Circle, Dead Men’s Boots… am I forgetting some, or does he have a new one out?
Thicker Than Water is the fourth book in the Felix Castor series. It’s not at my library and I think maybe it’s not out yet in the US, though I’ve seen contradictory info.
And The Naming of the Beasts is the fifth Felix Castor book. 
And if you’re looking for female-oriented urban fantasy that isn’t a Harlequin romance, the Kitty Norville series by Carrie Vaughn (starting with Kitty and the Midnight Hour) is pretty good. Up to seven or eight books now, I think.