Yeah, the artsy one is great!
I know none of you will believe this, but I SWEAR this plate exists:
IMPECHW
I saw it on an SUV (Pathfinder, I think) about a month ago, cruising down the 805 in San Diego.
I am NOT making that up. I damn near drove off the road.
On a Mini-Cooper in my parts: OBHAIV
Seen in the Central Valley of California on a minivan:
ANALOVE
I’m quite sure the woman (presumably named Ana) driving was oblivious to any additional interpretations of her plate…or maybe not… 
I thought my Dad’s was pretty clever. RXN. He drove an RX-7 to the Pharmacy that he worked at where he filled drug prescriptions (Rx’s).
Along those lines. My Mom is an Artist and my father a Pharmacist. They briefly discussed getting a personlised plate that read PHART, or PH-ART. He then chose RXN instead. Thankfully.
On a Land Rover: IGONEWAR
On Pink old-style Beetle: TICKLED
On a fuchsia Civic, with a Hello Kitty shade: 6RLYRYDE
On an older Jeep, parked a few blocks from I-66: IH8 66
On a white minivan, owned by an ex-federal employee: ANARKI
On an Infiniti --> ANDBYND
I have friends who have EMAIL and BOFH.
I forgot one more that made me laugh.
NARF
The license plate ring said “Are you pondering what I’m pondering?”
After I finished laughing, I said (to myself) “I think so Brain, but burlap chafes me so.” And then I laughed some more.
I work for NASA. and if I can get it, I want AG33K
My favorite: YOURN.
Makes no sense, of course, until one final fact is revealed:
The car owner is a urologist
I have some friends of the family who have an Infiniti with the license plate N BEYOND
I don’t get this… oh wait. “Impeach Dubya?”
It would work better if “your” and the first syllable un “urine” rhymed… or do they in your dialect?
Summary of a Reader’s Digest anecdote:
A woman called her doctor’s office to complain about a bill and wanted it it broken up item-by-item. When the nurse got down to “urinalysis”, the woman asked, “I’m a what?”
I think I’ve posted this around here before, but the best plates I’ve seen are:
DCY4THS
I spent an entire traffic light cycle figuring that one out, then laughed out loud when I got it. 
My plates are personalized, but they only make sense if you know my last name. I hope to someday have plates that say 8675309 (which would then make it easy to guess my first name 
).
IML8IML8
-mdf
When in grad school I used to walk through a parking lot on the way to my office. There was always the same car parked there with the license plate, “BAAB”. Didn’t think much of it until I connected that to the make of the car…Saab.
Great posts! More I’ve seen:
STILDNCN (outside an abortion clinic)
BLACKURA (Yes on a black Accura)(driven by a man of color)
IVADREAM Being passed on I-95 in Va. by
DREAMON
A car in my old home town had
IB6UB9
I didn’t see this plate. I was talking to a woman at a party once who owned a '69 Corvette. She loved her 'Vette and was very proud of it. She wanted a vanity plate that would show that. She came up with HEY 69.
She quickly learned it was possible to return vanity plates.
Probably about 20 years ago, in the L.A. area:
CYNTL8N
GR8 2SH
As was mentioned above, you can now replace one of the letters with a heart. Also available are stars, hands, and another one which I can’t remember. The DMV calls these child plates; the extra money goes to children’s charities. But I don’t see many vanity plates that just use the old format of up to 7 numerals or letters.
In the beginning, vanity plates had upper middle class connotations and you were always seeing them on BMWs, Mercedes, and so forth. I had my initials on my plate, first on a new VW then on an old Beemer. Now, though, they seem to have become passe. By the time I saw a license plate that said,
MI HNDAI
I decided that maybe it wasn’t so distinctive anymore.
You can still get traditional vanity plates, but I the DMV here offers a variety of other “special interest” plates, in addition to the child plates, that have different backgrounds. I think those are more popular these days.