Just in case you wanted to take a geographical tour:
Sleepy Hollow, The Witches of Eastwick – New England
Good Will Hunting – Boston’s South Side and Cambridge area
Jaws – Cape Cod
Mystic Pizza – Mystic, Connecticut
Crossing Delancey, Smithereens, I Shot Andy Warhol – Manhattan’s Lower East Side
Saturday Night Fever – Brooklyn, Manhattan
Annie Hall, Manhattan, Husbands and Wives – the Upper West Side
The Cotton Club – Harlem
The Taking of Pelham, One, Two, Three – the NYC subway system
Die Hard: With a Vengeance – NYC
Desperately Seeking Susan, Married To The Mob – Staten Island, the Lower East Side, and Miami Beach
Working Girl – Staten Island and Manhattan
Atlantic City – A.C., New Jersey
Clerks – suburban New Jersey
Trading Places, Philadelphia – Philly
Witness – Philly & Lancaster County, PA
Wonder Boys – Pittsburgh
Diner, Avalon, Pink Flamingos, Hairspray (and anything else ever directed by Barry Levinson or John Waters) – Baltimore
Out of Sight – Detroit, Souch Beach (Miami), and a couple of federal pens
Roger & Me – Flint, MI & Detroit
Hoosiers, Breaking Away – Indiana
The Last of the Mohicans – set in New York (I think), but filmed in Appalachian Mountains
October Sky – an Appalachian coal-mining town
Cape Fear – South Carolina? Louisiana?
Midnight In the Garden of Good and Evil – Savannah, GA
Sunshine State – Florida Panhandle (NE corner)
Body Heat – Palm Beach county
Miami Blues, The Specialist – Miami
The Big Easy – N’awlins
Bonnie & Clyde – various points in the Southwest
The Last Picture Show – rural, neo-Dustbowl Texas
Slacker – Austin, TX
The Right Stuff – California, Houston, Cape Canaveral
The Maltese Falcon, Bullitt, Invasion of the Body Snatchers ['78 remake], Tales from the City [TV miniseries] – San Fran
Greed (1924) – San Francisco? and Death Valley
High Sierra – the Sierra Nevadas
Chinatown, L.A. Confidential, Who Framed Roger Rabbitt?, Devil In A Blue Dress,… (mid-20th-C. L.A.)
Animal House – Oregon-standing-in-as-a-NE college
Twin Peaks [miniseries] – either Oregon or Washington state
Singles – Seattle
A River Runs Through It – Montana
Grumpy (and Grumpier) Old Men – Wabasha, Minnesota
Fargo – Fargo, N.D.
Roger & Me – Flint, Michigan
North By Northwest – from Manhattan to South Dakota
Some Like It Hot, While You Were Sleeping, Barbershop, Chicago – Chicago
The Blues Brothers – various points around Illinois and Chicago
The Bridges of Madison County – Iowa
Flirting With Disaster – NYC, Detroit, Alabama?, New Mexico (and a very funny movie, too)
Diamonds Are Forever – Las Vegas, Baja (“Ba-ha-ha”) California (Mexico)
Goldfinger – Miami Beach, Kentucky (Fort Knox)
Mars Attacks! – Washington, D.C., Las Vegas
Key omissions: Kansas City (MO), Memphis, Atlanta (something other than GWTW?), Colorado, Arizona, Maine, Key West, Alaska, Hawaii, the Rockies, and a good movie set around the Grand Canyon (Kasdan’s “Grand Canyon” doesn’t cut it).
American subcultures, obsessives, workaholics, etc.: Clerks, Trekkies (documentary), Best In Show & A Mighty Wind, Freaks, Carnies, A Texas Chainsaw Massacre, The Breakfast Club, Tucker: A Man and His Dream, Ed Wood, The Paper Chase, Dark Star, Escape From Alcatraz, Fast, Cheap & Out of Control (documentary),…
Sports: Paper Lion, North Dallas Forty, Hoosiers, Slap Shot, Miracle, A League of Their Own, A Field of Dreams, Bull Durham, Tin Cup,…