In IMHO since I’m sure different people have different tolerances/limits.
What is the least reprehensible action or crime one can commit where you think that the perpetrator has lost all claim on second chances, and doesn’t deserve redemption in your eyes? And what do you think society should do, if anything, to such people?
None. If a person chooses to become a good person then they can reform*. If a person is incapable of reforming then they are mentally ill, and therefore not fully to blame.
Theoretically. It doesn’t mean they actually will of course.