Short-term:
UNC will lose to Duke in the final seconds by one point.
Oh, wait… danggit, that was LAST night.
Ooops… my bad.
OK, Romney wins the nomination and loses to Mr. Obama by 12%.
Europe stabilizes but only after enacting significant austerity measures including limiting some social programs.
Greece votes to stay in the EU even after significant political opposition.
International terrorism will continue to be a growth industry, but the people of the USA will push back very hard if they feel that their individual rights are being abriged more than they have allowed up to now. If things get anymore restrictive, you will see a significant backlash.
China announces that it is planning a mission to Luna and also intends to have a permanent station there. Not a colony, yet. More like an Antarctic station. They describe this as a scientific mission.
Australia suffers a years long drought that causes it to need international assistance in some locations.
Arctic ice floes will diminish in size so that the Northwest Passage will become useful for several months of the year. Polar bears will become an endangered species. (They are currently ‘vulnerable’, so this is actually an easy one.)
Tablet PCs will outstrip sales of laptops and become the standard method of transporting your computing environment. Docking stations will become common with widescreen TVs doubling as large monitors at HD definition and keyboard/mouse as wireless peripherals. These will also incorporate your texting/phone functions.
Low emission/high efficiency automobiles will become the standard rather than an outlier. SUV’s will be as rare as wood-sided station wagons. Electric scooters might make a comeback. Depends on how high the gas prices go.
Oh, and yes, gasoline/petrol will cost more than $5 a gallon.
Medium term:
Eventually, after being embarrassed by the ongoing development of the Chinese lunar base, a consortium is created by the USA and members of the EU along with Australia (just now recovering from the economic crisis caused by the Great Drought), South Africa and India to create a lunar base of their own. Russia apparently has been working on this for a while and intends to create a base of their own.
Almost all cancers are curable if caught early enough. Regular cancer screenings become a home applied test much as pregnancy tests are done now. Health care in the USA finally becomes universal under the ‘common welfare’ concept. Longevity climbs so that 100+ is the excepted norm for life expectancy. STDs, including AIDS are curable and, in fact, preventable via vaccine-like treatments.
A general increase in health leads to a strong growth trend in what is now called the 3rd world nations. This will lead to an increase in GDP for many of these nations and will propel them into what is now called the 1st world nations.
Life of some kind will be found on Mars by a robotic probe. Its genetic material will be similar but not identical to that found in all Terran species. There will be a heated debate about whether they came from a single source or from dissimilar ones. A Mars mission is planned but underfunded and almost stalls but is finally given financing from several multi-billionaires who made money during the tablet craze of the early decades of the century.